Browsing Toxins By Category
Displaying toxin 901 - 925 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D4257 | Oxoadipic acid 3184-35-8 | C6H8O5 160.125 g/mol |  |
| In the matrix of mitochondria, 2-oxoadipate is decarboxylated to glutaryl-CoA by the 2-oxoadipate dehydrogenase complex and then converted to acetyl-CoA. Accumulation ...more Number of Targets: 1 |
| T3D2722 | Oxiconazole 64211-46-7 | C18H13Cl4N3O 429.127 g/mol |  |
| Oxiconazole inhibits ergosterol biosynthesis, which is required for cytoplasmic membrane integrity of fungi. It acts to destabilize the fungal cyctochrome P450 51 enzy...more Number of Targets: 1 |
| T3D2887 | Oxcarbazepine 28721-07-5 | C15H12N2O2 252.268 g/mol |  |
| The exact mechanism by which oxcarbazepine exerts its anticonvulsant effect is unknown. It is known that the pharmacological activity of oxcarbazepine occurs primarily...more Number of Targets: 1 |
| T3D4651 | Oxazolam 24143-17-7 | C18H17ClN2O2 328.793 g/mol |  |
| Benzodiazepines bind nonspecifically to benzodiazepine receptors BNZ1, which mediates sleep, and BNZ2, which affects affects muscle relaxation, anticonvulsant activity...more Number of Targets: 18 |
| T3D2909 | Oxazepam 604-75-1 | C15H11ClN2O2 286.713 g/mol |  |
| Similar to other benzodiazepines, oxazepam exerts its anxiolytic effects by potentiating the effect of gamma-aminobutyric acid (GABA) on GABA-A receptors through a coo...more Number of Targets: 24 |
| T3D3895 | Oxasulfuron 144651-06-9 | C17H18N4O6S 406.413 g/mol |  |
| Not Available Number of Targets: 2 |
| T3D0992 | Oxamyl 23135-22-0 | C7H13N3O3S 219.261 g/mol |  |
| Oxamyl is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylation of the active sites of ...more Number of Targets: 5 |
| T3D2674 | Oxaliplatin 61825-94-3 | C8H12N2O4Pt 395.276 g/mol |  |
| Oxaliplatin undergoes nonenzymatic conversion to active derivatives via displacement of the labile oxalate ligand. Several transient reactive species are formed, inclu...more Number of Targets: 1 |
| T3D0856 | Oxalic acid 144-62-7 | C2H2O4 90.035 g/mol |  |
| The affinity of divalent metal ions is sometimes reflected in their tendency to form insoluble precipitates. Thus in the body, oxalic acid also combines with metals io...more Number of Targets: 6 |
| T3D3894 | Oxadiazon 19666-30-9 | C15H18Cl2N2O3 345.221 g/mol |  |
| 'Oxadiazon is a member of the oxadiazole class of herbicides. While current data are limited, EPA has evidence that compounds within a class may share a common mechani...more Number of Targets: 9 |
| T3D0631 | Ovalene 190-26-1 | C32H14 398.454 g/mol |  |
| The ability of PAH's to bind to blood proteins such as albumin allows them to be transported throughout the body. Many PAH's induce the expression of cytochrome P450 e...more Number of Targets: 3 |
| T3D4018 | Ouabain 630-60-4 | C29H44O12 584.653 g/mol |  |
| Ouabain inhibits the Na-K-ATPase membrane pump, resulting in an increase in intracellular sodium and calcium concentrations. Increased intracellular concentrations of ...more Number of Targets: 6 |
| T3D4522 | Oryzalin 19044-88-3 | C12H18N4O6S 346.360 g/mol |  |
| Not Available Number of Targets: 18 |
| T3D3005 | Orphenadrine 83-98-7 | C18H23NO 269.381 g/mol |  |
| Orphenadrine binds and inhibits both histamine H1 receptors and NMDA receptors. It restores the motor disturbances induced by neuroleptics, in particular the hyperkine...more Number of Targets: 16 |
| T3D4292 | Orotic acid 65-86-1 | C5H4N2O4 156.096 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D2451 | Orellanine 37338-80-0 | C10H8N2O6 252.180 g/mol |  |
| Bipyridines with charged nitrogen atoms confound important redox reactions in organisms, ‘stealing’ one or two electrons and sometimes bypass the electrons into other ...more Number of Targets: 0 |
| T3D2925 | Ondansetron 99614-02-5 | C18H19N3O 293.363 g/mol |  |
| Ondansetron is a selective serotonin 5-HT3 receptor antagonist. The antiemetic activity of the drug is brought about through the inhibition of 5-HT3 receptors present ...more Number of Targets: 15 |
| T3D2550 | Onchidal 67656-42-2 | C17H24O3 276.371 g/mol |  |
| Onchidal is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinestera...more Number of Targets: 1 |
| T3D0991 | Oms 22 3566-09-4 | C11H14ClNO2 227.687 g/mol |  |
| Oms 22 is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylation of the active sites of ...more Number of Targets: 2 |
| T3D3524 | Omeprazole 73590-58-6 | C17H19N3O3S 345.416 g/mol |  |
| Omeprazole is a proton pump inhibitor that suppresses gastric acid secretion by specific inhibition of the H+/K+-ATPase in the gastric parietal cell. By acting specifi...more Number of Targets: 6 |
| T3D2656 | omega-Conotoxin (Conus striatus) Not Available | Not Available 7628.040 g/mol |  |
| omega-Conotoxins act at presynaptic membranes, where they bind inhibit N-type voltage-dependent calcium channels. (L1107) Number of Targets: 1 |
| T3D2494 | omega-Agatoxin 145017-83-0 | Not Available 12807.575 g/mol |  |
| omega-Agatoxins block the calcium channels in the presynaptic terminals of the neuromuscular junction in insects and vertebrates. This reduces calcium influx, resultin...more Number of Targets: 1 |
| T3D2886 | Olopatadine 113806-05-6 | C21H23NO3 337.412 g/mol |  |
| Olopatadine is a selective histamine H1 antagonist that binds to the histamine H1 receptor. This blocks the action of endogenous histamine, which subsequently leads to...more Number of Targets: 6 |
| T3D4802 | Oleic acid 112-80-1 | C18H34O2 282.461 g/mol |  |
| Not Available Number of Targets: 5 |
| T3D3094 | Oleandrin 465-16-7 | C32H48O9 576.718 g/mol |  |
| Oleandrin likely exerts its toxic effects by inhibiting Na+,K+-ATPase. (A2831) Number of Targets: 9 |