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Displaying toxin 1801 - 1825 of 3678 in total
T3DB ID Name
CAS Number
Formula
Weight
StructureTypeMechanism of Toxicity
T3D2549Eledoisin (Eledone cirrhosa)
69-25-0
Not Available
1206.410 g/mol
T3d2549
  • Amide
  • Amine
  • Animal Toxin
  • Marine Toxin
  • Natural Compound
  • Organic Compound
  • Protein
Eledoisin is a tachykinin peptide. Tachykinins excite neurons, evoke behavioural responses, are potent vasodilators and secretagogues, and contract (directly or indire...more
Number of Targets: 3
T3D4977Edetic Acid
62-33-9
C10H16N2O8
292.243 g/mol
Thumb
  • Anticoagulant
  • Chelating Agent
  • Drug
  • Food Additive
  • Metabolite
  • Synthetic Compound
The pharmacologic effects of edetate calcium disodium are due to the formation of chelates with divalent and trivalent metals. A stable chelate will form with any meta...more
Number of Targets: 3
T3D2592Edema factor
921236-86-4
Not Available
92477.285 g/mol
T3d2592
  • Amide
  • Amine
  • Bacterial Toxin
  • Natural Compound
  • Organic Compound
  • Protein
After binding to a host cell surface receptor, PA is cleaved by membrane endoproteases of the furin family. Cleaved PA molecules assemble into heptamers, which then as...more
Number of Targets: 7
T3D2992Econazole
27220-47-9
C18H15Cl3N2O
381.684 g/mol
Thumb
  • Amine
  • Antifungal Agent
  • Drug
  • Ether
  • Metabolite
  • Organic Compound
  • Organochloride
  • Synthetic Compound
Econazole interacts with 14-α demethylase, a cytochrome P-450 enzyme necessary to convert lanosterol to ergosterol. As ergosterol is an essential component of the fung...more
Number of Targets: 4
T3D2805Duloxetine
136434-34-9
C18H19NOS
297.415 g/mol
Thumb
  • Adrenergic Uptake Inhibitor
  • Amine
  • Antidepressant
  • Dopamine Uptake Inhibitor
  • Drug
  • Ether
  • Metabolite
  • Organic Compound
  • Serotonin Uptake Inhibitor
  • Synthetic Compound
Duloxetine is a potent inhibitor of neuronal serotonin and norepinephrine reuptake and a less potent inhibitor of dopamine reuptake. Duloxetine has no significant affi...more
Number of Targets: 3
T3D2917Drostanolone
58-19-5
C20H32O2
304.467 g/mol
Thumb
  • Anabolic Agent
  • Antineoplastic Agent, Hormonal
  • Drug
  • Ester
  • Ether
  • Metabolite
  • Organic Compound
  • Synthetic Compound
Dromostanolone is a synthetic androgenic anabolic steroid and is approximately 5 times as potent as natural methyltestosterone. Like testosterone and other androgenic ...more
Number of Targets: 4
T3D4551Doxylamine
469-21-6
C17H22N2O
270.369 g/mol
Thumb
  • Amine
  • Antiemetic
  • Drug
  • Ether
  • Food Toxin
  • Histamine H1 Antagonist
  • Organic Compound
  • Synthetic Compound
Like other antihistamines, doxylamine acts by competitively inhibiting histamine at H1 receptors. It also has substantial sedative and anticholinergic effects.
Number of Targets: 3
T3D3950Doxycycline
564-25-0
C22H24N2O8
444.435 g/mol
Thumb
  • Anti-Bacterial Agent
  • Antimalarial
  • Drug
  • Metabolite
  • Organic Compound
  • Synthetic Compound
  • Tetracycline
Tetracyclines target the 28S small subunit of the mitochondrial ribosome thereby deactivation mitochondrial protein synthesis. As a result tetracyclines are cytotoxic ...more
Number of Targets: 3
T3D2953Doxorubicin
23214-92-8
C27H29NO11
543.519 g/mol
Thumb
  • Amine
  • Antibiotic
  • Antibiotic, Antineoplastic
  • Antineoplastic Agent
  • Drug
  • Ester
  • Ether
  • Metabolite
  • Organic Compound
  • Synthetic Compound
Doxorubicin has antimitotic and cytotoxic activity through a number of proposed mechanisms of action: Doxorubicin forms complexes with DNA by intercalation between bas...more
Number of Targets: 14
T3D2993Doxepin
1668-19-5
C19H21NO
279.376 g/mol
Thumb
  • Adrenergic Uptake Inhibitor
  • Amine
  • Anti-Anxiety Agent
  • Antidepressant
  • Antidepressive Agent
  • Antidepressive Agent, Tricyclic
  • Antipruritic
  • Drug
  • Ether
  • Histamine Antagonist
  • Metabolite
  • Norepinephrine Reuptake Inhibitor
  • Organic Compound
  • Synthetic Compound
The mechanism of action of doxepin is not completely understood. It is thought that like amitriptyline, doxepin enhances the actions of norepinephrine and serotonin by...more
Number of Targets: 23
T3D4646Doxefazepam
40762-15-0
C17H14ClFN2O3
348.756 g/mol
Thumb
  • Amide
  • Amine
  • Drug
  • Organic Compound
  • Organochloride
  • Organofluoride
  • Synthetic Compound
Benzodiazepines bind nonspecifically to benzodiazepine receptors BNZ1, which mediates sleep, and BNZ2, which affects affects muscle relaxation, anticonvulsant activity...more
Number of Targets: 18
T3D4300Dopamine
51-61-6
C8H11NO2
153.178 g/mol
Thumb
  • Amine
  • Animal Toxin
  • Cardiotonic Agent
  • Dopamine Agent
  • Drug
  • Food Toxin
  • Metabolite
  • Natural Compound
  • Organic Compound
  • Sympathomimetic
Dopamine is a precursor to norepinephrine in noradrenergic nerves and is also a neurotransmitter in certain areas of the central nervous system. Dopamine produces posi...more
Number of Targets: 15
T3D2910Donepezil
120014-06-4
C24H29NO3
379.492 g/mol
Thumb
  • Amine
  • Cholinesterase Inhibitor
  • Drug
  • Ester
  • Ether
  • Food Toxin
  • Metabolite
  • Nootropic Agent
  • Organic Compound
  • Parasympathomimetic
  • Synthetic Compound
Donepezil is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinester...more
Number of Targets: 4
T3D4040Domoic acid
14277-97-5
C15H21NO6
311.330 g/mol
Thumb
  • Amine
  • Animal Toxin
  • Food Toxin
  • Marine Toxin
  • Metabolite
  • Natural Compound
  • Organic Compound
Domoic acid acts as a neurotoxin. It induces excitotoxicity by an integrative action on ionotropic glutamate receptors at both sides of the synapse for which it has hi...more
Number of Targets: 1
T3D4904Dodecyl gallate
1166-52-5
C19H30O5
338.439 g/mol
Thumb
  • Ester
  • Ether
  • Food Additive
  • Food Toxin
  • Metabolite
  • Organic Compound
  • Synthetic Compound
Not Available
Number of Targets: 4
T3D4596Dodecanoic acid
143-07-7
C12H24O2
200.318 g/mol
Thumb
  • Food Toxin
  • Household Toxin
  • Metabolite
  • Natural Compound
  • Organic Compound
  • Plant Toxin
Not Available
Number of Targets: 13
T3D3501Docetaxel
114977-28-5
C43H53NO14
807.879 g/mol
Thumb
  • Amine
  • Antimalarial
  • Antineoplastic Agent
  • Antineoplastic Agent, Phytogenic
  • Drug
  • Ester
  • Ether
  • Metabolite
  • Organic Compound
  • Radiation-Sensitizing Agent
  • Synthetic Compound
Docetaxel interferes with the normal function of microtubule growth. Whereas drugs like colchicine cause the depolymerization of microtubules in vivo, docetaxel arrest...more
Number of Targets: 9
T3D3079Djenkolic acid
498-59-9
C7H14N2O4S2
254.327 g/mol
Thumb
  • Amine
  • Ether
  • Natural Compound
  • Organic Compound
  • Plant Toxin
The toxicity of djenkolic acid in humans arises from its poor solubility under acidic conditions after consumption of the jenkol bean. The amino acid precipitates into...more
Number of Targets: 0
T3D4500Diuron
330-54-1
C9H10Cl2N2O
233.095 g/mol
Thumb
  • Amine
  • Herbicide
  • Household Toxin
  • Organic Compound
  • Organochloride
  • Pesticide
  • Synthetic Compound
Diuron has been reported to bind to androgen receptors. This suggests that diuron may block the receptors and result in the toxicity on the reproductive system.
Number of Targets: 8
T3D3657Diundecyl phthalate
3648-20-2
C30H50O4
474.716 g/mol
Thumb
  • Aromatic Hydrocarbon
  • Cosmetic Toxin
  • Ester
  • Ether
  • Food Toxin
  • Household Toxin
  • Industrial/Workplace Toxin
  • Organic Compound
  • Phthalate
  • Plasticizer
  • Synthetic Compound
Phthalate esters are endocrine disruptors. They decrease foetal testis testosterone production and reduce the expression of steroidogenic genes by decreasing mRNA expr...more
Number of Targets: 0
T3D3656Ditridecyl phthalate
119-06-2
C34H58O4
530.822 g/mol
Thumb
  • Aromatic Hydrocarbon
  • Cosmetic Toxin
  • Ester
  • Ether
  • Food Toxin
  • Household Toxin
  • Industrial/Workplace Toxin
  • Organic Compound
  • Phthalate
  • Plasticizer
  • Synthetic Compound
Phthalate esters are endocrine disruptors. They decrease foetal testis testosterone production and reduce the expression of steroidogenic genes by decreasing mRNA expr...more
Number of Targets: 0
T3D4499Dithiopyr
97886-45-8
C15H16F5NO2S2
401.415 g/mol
Thumb
  • Ester
  • Ether
  • Herbicide
  • Household Toxin
  • Organic Compound
  • Organofluoride
  • Pesticide
  • Synthetic Compound
Not Available
Number of Targets: 18
T3D0038Disulfoton
298-04-4
C8H19O2PS3
274.404 g/mol
Thumb
  • Ester
  • Ether
  • Household Toxin
  • Organic Compound
  • Organophosphate
  • Pesticide
  • Synthetic Compound
Disulfoton is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholineste...more
Number of Targets: 6
T3D2557Disulfiram
97-77-8
C10H20N2S4
296.539 g/mol
Thumb
  • Alcohol Deterrent
  • Amine
  • Drug
  • Enzyme Inhibitor
  • Metabolite
  • Organic Compound
  • Synthetic Compound
Disulfiram blocks the oxidation of alcohol at the acetaldehyde stage during alcohol metabolism following disulfiram intake causing an accumulation of acetaldehyde in t...more
Number of Targets: 24
T3D4862Disodium 6-hydroxy-5-[(4-sulfophenyl)azo]-2-naphthalenesulfonate
2783-94-0
C16H12N2Na2O7S2
454.384 g/mol
Thumb
  • Dye
  • Food Additive
  • Food Toxin
  • Household Toxin
  • Metabolite
  • Organic Compound
  • Synthetic Compound
Not Available
Number of Targets: 1
Displaying toxin 1801 - 1825 of 3678 in total