Browsing Toxins By Category
Displaying toxin 1876 - 1900 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D2750 | Dihydroergotamine 6190-39-2 | C33H37N5O5 583.677 g/mol |  |
| Two theories have been proposed to explain the efficacy of 5-HT1D receptor agonists in migraine: 1) activation of 5-HT1D receptors located on intracranial blood vessel...more Number of Targets: 12 |
| T3D3683 | Dihydrocytochalasin B gamma-lactone 14110-71-5 | C29H39NO5 481.624 g/mol |  |
| Cytochalasins are known to bind to the barbed, fast growing plus ends of microfilaments, which then blocks both the assembly and disassembly of individual actin monome...more Number of Targets: 6 |
| T3D3682 | Dihydrocytochalasin B 39156-67-7 | C28H37NO5 467.597 g/mol |  |
| Cytochalasins are known to bind to the barbed, fast growing plus ends of microfilaments, which then blocks both the assembly and disassembly of individual actin monome...more Number of Targets: 6 |
| T3D4987 | Dihydro-5-propyl-2(3H)-furanone 57129-71-2 | C7H12O2 128.169 g/mol |  |
| Not Available Number of Targets: 0 |
| T3D2670 | Digoxin 20830-75-5 | C41H64O14 780.939 g/mol |  |
| Digoxin binds to a site on the extracellular aspect of the alpha-subunit of the Na+/K+ ATPase pump in the membranes of heart cells (myocytes) and decreases its functio...more Number of Targets: 17 |
| T3D4021 | Digitoxin 71-63-6 | C41H64O13 764.939 g/mol |  |
| Digitoxin inhibits the Na-K-ATPase membrane pump, resulting in an increase in intracellular sodium and calcium concentrations. Increased intracellular concentrations o...more Number of Targets: 2 |
| T3D2918 | Diflunisal 22494-42-4 | C13H8F2O3 250.198 g/mol |  |
| The precise mechanism of the analgesic and anti-inflammatory actions of diflunisal is not known. Diflunisal is a prostaglandin synthetase inhibitor. In animals, prosta...more Number of Targets: 7 |
| T3D4921 | Diflubenzuron 35367-38-5 | C14H9ClF2N2O2 310.683 g/mol |  |
| One of the metabolites of diflubenzuron, PCA, is a proximate carcinogen. It is conjugated to form the carcinogen that can ionize and reat with DNA to form adducts whic...more Number of Targets: 2 |
| T3D3829 | Difenzoquat metilsulfate 43222-48-6 | C18H20N2O4S 360.427 g/mol |  |
| Difenzoquat metilsulfate is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of ac...more Number of Targets: 21 |
| T3D3828 | Difenoconazole 119446-68-3 | C19H17Cl2N3O3 406.263 g/mol |  |
| Not Available Number of Targets: 30 |
| T3D3104 | Difenacoum 56073-07-5 | C31H24O3 444.521 g/mol |  |
| Difenacoum inhibits the enzyme Vitamin K epoxide reductase. This enzyme is needed for the reconstitution of the vitamin K in its cycle from vitamin K-epoxide, and so d...more Number of Targets: 1 |
| T3D0748 | Diethylzinc 557-20-0 | C4H10Zn 123.531 g/mol |  |
| Anaemia results from the excessive absorption of zinc suppressing copper and iron absorption, most likely through competitive binding of intestinal mucosal cells. Unba...more Number of Targets: 1 |
| T3D3827 | Diethyltoluamide 134-62-3 | C12H17NO 191.270 g/mol |  |
| Not Available Number of Targets: 3 |
| T3D3958 | Diethylthiophosphate 5871-17-0 | C4H11O3PS 170.167 g/mol |  |
| Diethylthiophosphate (DETP) induces DNA damage only in the hepatic cell lines, and this effect could be related to a secondary non-diffusible metabolite generated by t...more Number of Targets: 1 |
| T3D4744 | Diethylstilbestrol 56-53-1 | C18H20O2 268.350 g/mol |  |
| Estrogens diffuse into their target cells and interact with a protein receptor, the estrogen receptor. Target cells include the female reproductive tract, the mammary ...more Number of Targets: 9 |
| T3D2935 | Diethylpropion 90-84-6 | C13H19NO 205.296 g/mol |  |
| Diethylpropion is an amphetamine that stimulates neurons to release or maintain high levels of a particular group of neurotransmitters known as catecholamines; these i...more Number of Targets: 2 |
| T3D3969 | Diethylphosphate 598-02-7 | C4H11O4P 154.102 g/mol |  |
| S-Ethylisothiouronium diethylphosphate is a specific inhibitor of inducible NO synthase on hepatic NO production level. S-Ethylisothiouronium diethylphosphate affects ...more Number of Targets: 1 |
| T3D4901 | Diethylenetriamine 111-40-0 | C4H13N3 103.166 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D1338 | Diethyldimethyl lead 1762-27-2 | C6H16Pb 295.400 g/mol |  |
| Lead mimics other biologically important metals, such as zinc, calcium, and iron, competing as cofactors for many of their respective enzymatic reactions. For example,...more Number of Targets: 29 |
| T3D4214 | Diethylamine 71247-25-1 | C4H11N 73.137 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D3638 | Diethyl phthalate 84-66-2 | C12H14O4 222.237 g/mol |  |
| Phthalate esters are endocrine disruptors. They decrease foetal testis testosterone production and reduce the expression of steroidogenic genes by decreasing mRNA expr...more Number of Targets: 10 |
| T3D1358 | Diethyl mercury 627-44-1 | C4H10Hg 258.710 g/mol |  |
| High-affinity binding of the divalent mercuric ion to thiol or sulfhydryl groups of proteins is believed to be the major mechanism for the activity of mercury. Through...more Number of Targets: 50 |
| T3D0959 | Diethofencarb 87130-20-9 | C14H21NO4 267.321 g/mol |  |
| Diethofencarb is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylation of the active si...more Number of Targets: 2 |
| T3D4845 | Diethanolamine 111-42-2 | C4H11NO2 105.136 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D0017 | Dieldrin 60-57-1 | C12H8Cl6O 380.909 g/mol |  |
| Dieldrin antagonizes the action of the neurotransmitter gamma-aminobutyric acid (GABA) acting at the GABA-A receptors, effectively blocking the GABA-induced uptake of ...more Number of Targets: 46 |