Browsing Toxins By Category
Displaying toxin 1751 - 1775 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D1010 | Terbucarb 1918-11-2 | C17H27NO2 277.402 g/mol |  |
| Terbucarb is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylation of the active sites ...more Number of Targets: 2 |
| T3D0998 | Promacyl 34264-24-9 | C16H23NO3 277.359 g/mol |  |
| Promacyl is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylation of the active sites o...more Number of Targets: 2 |
| T3D4677 | Azathioprine 446-86-6 | C9H7N7O2S 277.263 g/mol |  |
| Azathioprine antagonizes purine metabolism and may inhibit synthesis of DNA, RNA, and proteins. It may also interfere with cellular metabolism and inhibit mitosis. Its...more Number of Targets: 1 |
| T3D3839 | Fenitrothion 122-14-5 | C9H12NO5PS 277.234 g/mol |  |
| Fenitrothion is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholines...more Number of Targets: 16 |
| T3D0792 | Crocidolite Asbestos 12001-28-4 | (Na, K)0-1Na2Fe3+2Mg3Si8O22(OH)2 Not Available |  |
| When asbestos fibers are inhaled, many are deposited on the epithelial surface of the respiratory tree. Fibers that are retained in the lung or mesothelium for long pe...more Number of Targets: 1 |
| T3D0119 | Chrysotile asbestos 12001-29-5 | Mg3Si2O5(OH)4 Not Available |  |
| When asbestos fibers are inhaled, many are deposited on the epithelial surface of the respiratory tree. Fibers that are retained in the lung or mesothelium for long pe...more Number of Targets: 1 |
| T3D1694 | Bromoxynil 1689-84-5 | C7H3Br2NO 276.913 g/mol |  |
| Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary mechanism of toxicity for organic nitriles is their production of toxi...more Number of Targets: 51 |
| T3D1126 | Barium zirconium oxide 12009-21-1 | BaO3Zr 276.549 g/mol |  |
| Barium is a competitive potassium channel antagonist that blocks the passive efflux of intracellular potassium, resulting in a shift of potassium from extracellular to...more Number of Targets: 21 |
| T3D2550 | Onchidal 67656-42-2 | C17H24O3 276.371 g/mol |  |
| Onchidal is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinestera...more Number of Targets: 1 |
| T3D0621 | Benzo[ghi]perylene 191-24-2 | C22H12 276.331 g/mol |  |
| The ability of PAH's to bind to blood proteins such as albumin allows them to be transported throughout the body. Many PAH's induce the expression of cytochrome P450 e...more Number of Targets: 3 |
| T3D0632 | Anthanthrene 191-26-4 | C22H12 276.331 g/mol |  |
| The ability of PAH's to bind to blood proteins such as albumin allows them to be transported throughout the body. Many PAH's induce the expression of cytochrome P450 e...more Number of Targets: 3 |
| T3D0174 | Indeno(1,2,3-cd)pyrene 193-39-5 | C22H12 276.331 g/mol |  |
| The ability of PAH's to bind to blood proteins such as albumin allows them to be transported throughout the body. Many PAH's induce the expression of cytochrome P450 e...more Number of Targets: 3 |
| T3D4398 | Saccharopine 997-68-2 | C11H20N2O6 276.286 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D4833 | Triethyl citrate 77-93-0 | C12H20O7 276.283 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D4063 | Ranunculin 644-69-9 | C11H16O8 276.240 g/mol |  |
| Ranunculin (RAN) inhibited the incorporation of 3H-labeled precursors into DNA and RNA of L1210 cells. RAN (15 mumol/L) markedly decreased DNA synthesis catalyzed by D...more Number of Targets: 0 |
| T3D4768 | Flutamide 13311-84-7 | C11H11F3N2O3 276.212 g/mol |  |
| Flutamide is a nonsteroidal antiandrogen that blocks the action of both endogenous and exogenous testosterone by binding to the androgen receptor. In addition Flutamid...more Number of Targets: 7 |
| T3D3830 | Dimethenamid 87674-68-8 | C12H18ClNO2S 275.795 g/mol |  |
| Not Available Number of Targets: 13 |
| T3D1466 | Zineb 12122-67-7 | C4H6N2S4Zn 275.773 g/mol |  |
| Anaemia results from the excessive absorption of zinc suppressing copper and iron absorption, most likely through competitive binding of intestinal mucosal cells. Unba...more Number of Targets: 1 |
| T3D1602 | Silver carbonate 534-16-7 | CAg2O3 275.745 g/mol |  |
| Metallic silver is oxidized and may deposit in the tissues, causing arygria. The silver ion is known to inhibit glutathione peroxidase and NA+,K+-ATPase activity, disr...more Number of Targets: 17 |
| T3D3793 | Anilazine 101-05-3 | C9H5Cl3N4 275.522 g/mol |  |
| Anilazine was found to be mutagenic. Number of Targets: 2 |
| T3D3885 | MGK 113-48-4 | C17H25NO2 275.386 g/mol |  |
| Not Available Number of Targets: 6 |
| T3D3862 | Imazapic 104098-48-8 | C14H17N3O3 275.303 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D4920 | Paraoxon 311-45-5 | C10H14NO6P 275.195 g/mol |  |
| Paraoxon is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinestera...more Number of Targets: 5 |
| T3D1293 | Acetarsol 97-44-9 | C8H10AsNO5 275.090 g/mol |  |
| Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co...more Number of Targets: 44 |
| T3D0683 | Bis(cyclooctadiene)nickel(0) 1295-35-8 | C16H24Ni 275.055 g/mol |  |
| Nickel is known to substitute for other essential elements in certain enzmes, such as calcineurin. It is genotoxic, and some nickel compounds have been shown to promot...more Number of Targets: 68 |