Browsing Toxins By Category
Displaying toxin 2476 - 2500 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D0504 | 2,3,4,4',6-Pentachlorobiphenyl 74472-38-1 | C12H5Cl5 326.433 g/mol |  |
| The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcriptio...more Number of Targets: 7 |
| T3D0505 | 2,3,4,5,6-Pentachlorobiphenyl 18259-05-7 | C12H5Cl5 326.433 g/mol |  |
| The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcriptio...more Number of Targets: 7 |
| T3D0506 | 2,3,4',5,6-Pentachlorobiphenyl 68194-11-6 | C12H5Cl5 326.433 g/mol |  |
| The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcriptio...more Number of Targets: 7 |
| T3D0507 | 2,3',4,4',5-Pentachlorobiphenyl 31508-00-6 | C12H5Cl5 326.433 g/mol |  |
| The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcriptio...more Number of Targets: 8 |
| T3D0508 | 2,3',4,4',6-Pentachlorobiphenyl 56558-17-9 | C12H5Cl5 326.433 g/mol |  |
| The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcriptio...more Number of Targets: 7 |
| T3D0509 | 2,3',4,5,5'-Pentachlorobiphenyl 68194-12-7 | C12H5Cl5 326.433 g/mol |  |
| The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcriptio...more Number of Targets: 7 |
| T3D0510 | 2,3',4,5',6-Pentachlorobiphenyl 56558-18-0 | C12H5Cl5 326.433 g/mol |  |
| The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcriptio...more Number of Targets: 7 |
| T3D1351 | Ethylmercuric phosphate 2235-25-8 | C2H7HgO4P 326.640 g/mol |  |
| High-affinity binding of the divalent mercuric ion to thiol or sulfhydryl groups of proteins is believed to be the major mechanism for the activity of mercury. Through...more Number of Targets: 50 |
| T3D1888 | Trimethylantimony bromide 5835-64-3 | C3H9Br2Sb 326.670 g/mol |  |
| The inhalation data suggests that the myocardium is a target of antimony toxicity. It is possible that antimony affects circulating glucose by interfering with enzymes...more Number of Targets: 26 |
| T3D2764 | Clozapine 5786-21-0 | C18H19ClN4 326.823 g/mol |  |
| The mechanism of action of Clozapine, as with other drugs used to treat schizophrenia, is unknown. However, it has been proposed that the drug's therapeutic activity i...more Number of Targets: 29 |
| T3D3891 | Niclosamide 50-65-7 | C13H8Cl2N2O4 327.120 g/mol |  |
| Niclosamide works by killing tapeworms on contact. Adult worms (but not ova) are rapidly killed, presumably due to uncoupling of oxidative phosphorylation or stimulati...more Number of Targets: 47 |
| T3D0680 | Salcomine 14167-18-1 | C16H16CoN2O2 327.244 g/mol |  |
| Cobalt is believed to exhibit its toxicity through a oxidant-based and free radical-based processes. It produces oxygen radicals and may be oxidized to ionic cobalt, c...more Number of Targets: 35 |
| T3D2837 | Butorphanol 42408-82-2 | C21H29NO2 327.461 g/mol |  |
| The exact mechanism of action is unknown, but is believed to interact with an opiate receptor site in the CNS (probably in or associated with the limbic system). The o...more Number of Targets: 3 |
| T3D3619 | Ammonium laureth sulfate 32612-48-9 | C14H33NO5S 327.481 g/mol |  |
| While ammonium laureth sulfate itself is not toxic, it is a nitrosating agent. Nitrosating agents may decompose and/or react to cause nitrosamine contamination. Nitros...more Number of Targets: 1 |
| T3D3921 | Sethoxydim 74051-80-2 | C17H29NO3S 327.482 g/mol |  |
| Not Available Number of Targets: 5 |
| T3D2328 | 6-tert-Butyl-1,3,8-trichlorodibenzofuran 125652-12-2 | C16H13Cl3O 327.633 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2779 | Loxapine 1977-10-2 | C18H18ClN3O 327.808 g/mol |  |
| Loxapine is a dopamine antagonist, and also a serotonin 5-HT2 blocker. The exact mode of action of Loxapine has not been established, however changes in the level of e...more Number of Targets: 33 |
| T3D2037 | 4,4'-Dibromobiphenyl Ether 2050-47-7 | C12H8Br2O 327.999 g/mol |  |
| Like other halogenated aromatic hydrocarbons, polybrominated diphenyl ethers bind to the cellular aryl hydrocarbon receptor (AhR), which regulates the synthesis of a v...more Number of Targets: 6 |
| T3D0346 | Mercury telluride 12068-90-5 | HgTe 328.200 g/mol |  |
| High-affinity binding of the divalent mercuric ion to thiol or sulfhydryl groups of proteins is believed to be the major mechanism for the activity of mercury. Through...more Number of Targets: 50 |
| T3D3666 | Aflatoxin M1 6795-23-9 | C17H12O7 328.273 g/mol |  |
| Aflatoxins produce singlet oxygen upon their exposure to UV (365-nm) light. Singlet oxygen in turn activates them to mutagens and DNA binding species. Aflatoxin M1 is ...more Number of Targets: 2 |
| T3D3670 | Aflatoxin G 1165-39-5 | C17H12O7 328.273 g/mol |  |
| Aflatoxins produce singlet oxygen upon their exposure to UV (365-nm) light. Singlet oxygen in turn activates them to mutagens and DNA binding species. Aflatoxin metabo...more Number of Targets: 1 |
| T3D3074 | Anisatin 5230-87-5 | C15H20O8 328.315 g/mol |  |
| Anisatin acts as a GABA system antagonist. It binds non-competitively to the picrotoxinin site of the GABA receptor, prolonging the closed time of the receptor channel...more Number of Targets: 19 |
| T3D3517 | Labetalol 36894-69-6 | C19H24N2O3 328.406 g/mol |  |
| Labetalol has two asymmetric centers and therefore, exists as a molecular complex of two diastereoisomeric pairs. Dilevalol, the R,R' stereoisomer, makes up 25% of rac...more Number of Targets: 7 |
| T3D1857 | Pyrethrin I 121-21-1 | C21H28O3 328.445 g/mol |  |
| Pyrethrins exert their effect by prolonging the open phase of the sodium channel gates when a nerve cell is excited. They appear to bind to the membrane lipid phase in...more Number of Targets: 20 |
| T3D3041 | Methotrimeprazine 60-99-1 | C19H24N2OS 328.472 g/mol |  |
| Methotrimeprazine's antipsychotic effect is largely due to its antagonism of dopamine receptors in the brain. In addition, its binding to 5HT2 receptors may also play ...more Number of Targets: 20 |