Browsing Toxins By Category
Displaying toxin 2676 - 2700 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D4738 | Encainide 66778-36-7 | C22H28N2O2 352.470 g/mol |  |
| Encainide is a sodium channel blocker, binding to voltage gated sodium channels. It stabilizes the neuronal membrane by inhibiting the ionic fluxes required for the in...more Number of Targets: 1 |
| T3D2893 | Halazepam 23092-17-3 | C17H12ClF3N2O 352.738 g/mol |  |
| Benzodiazepines bind nonspecifically to benzodiazepine receptors BNZ1, which mediates sleep, and BNZ2, which affects affects muscle relaxation, anticonvulsant activity...more Number of Targets: 18 |
| T3D4696 | Griseofulvin 126-07-8 | C17H17ClO6 352.766 g/mol |  |
| Griseofulvin is fungistatic, however the exact mechanism by which it inhibits the growth of dermatophytes is not clear. It is thought to inhibit fungal cell mitosis an...more Number of Targets: 1 |
| T3D4515 | Hexythiazox 78587-05-0 | C17H21ClN2O2S 352.879 g/mol |  |
| Not Available Number of Targets: 11 |
| T3D1892 | Triphenylantimony 603-36-1 | C18H15Sb 353.070 g/mol |  |
| The inhalation data suggests that the myocardium is a target of antimony toxicity. It is possible that antimony affects circulating glucose by interfering with enzymes...more Number of Targets: 20 |
| T3D3106 | Acenocoumarol 152-72-7 | C19H15NO6 353.326 g/mol |  |
| Acenocoumarol inhibits vitamin K reductase, resulting in depletion of the reduced form of vitamin K (vitamin KH2). As vitamin K is a cofactor for the carboxylation of ...more Number of Targets: 3 |
| T3D4087 | Chelidonine 476-32-4 | C20H19NO5 353.369 g/mol |  |
| Chelidonine is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinest...more Number of Targets: 0 |
| T3D4015 | Protopine 130-86-9 | C20H19NO5 353.369 g/mol |  |
| Protopine has been found to inhibit histamine H1 receptors and platelet aggregation, and acts as an analgesic. It is one of the compounds with activity like OPIATE ALK...more Number of Targets: 0 |
| T3D2726 | Methysergide 361-37-5 | C21H27N3O2 353.458 g/mol |  |
| Ergoline alkaloids have been shown to have the significant affinity towards the 5-HT1 and 5-HT2 serotonin receptors, D1 and D2 dopamine receptors, and alpha-adrenergic...more Number of Targets: 11 |
| T3D3027 | Levomethadyl Acetate 1477-40-3 | C23H31NO2 353.498 g/mol |  |
| Opiate receptors (Mu, Kappa, Delta) are coupled with G-protein receptors and function as both positive and negative regulators of synaptic transmission via G-proteins ...more Number of Targets: 3 |
| T3D2324 | 6-Cyclohexyl-1,3,8-trichlorodibenzofuran 125652-15-5 | C18H15Cl3O 353.670 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D3847 | Flumioxazin 103361-09-7 | C19H15FN2O4 354.332 g/mol |  |
| Not Available Number of Targets: 4 |
| T3D3707 | Fusarenon-X 23255-69-8 | C17H22O8 354.352 g/mol |  |
| Unlike many other mycotoxins, trichothecenes do not require metabolic activation to exert their biological activity, instead directly reacting with cellular components...more Number of Targets: 2 |
| T3D0800 | Rotenone 83-79-4 | C20H18O6 354.353 g/mol |  |
| Rotenone works by interfering with the electron transport chain in mitochondria. Specifically, it inhibits the transfer of electrons from iron-sulfur centers in comple...more Number of Targets: 47 |
| T3D1013 | Thiodicarb 59669-26-0 | C10H18N4O4S3 354.469 g/mol |  |
| Thiodicarb is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylation of the active sites...more Number of Targets: 17 |
| T3D0012 | Clofenotane 50-29-3 | C14H9Cl5 354.486 g/mol |  |
| DDT toxicity occurs via at least four mechanisms, possibly all functioning simultaneously. DDT reduces potassium transport across the membrane. DDT inhibits the inacti...more Number of Targets: 64 |
| T3D0050 | O,P'-DDT 789-02-6 | C14H9Cl5 354.486 g/mol |  |
| DDT toxicity occurs via at least four mechanisms, possibly all functioning simultaneously. DDT reduces potassium transport across the membrane. DDT inhibits inactivati...more Number of Targets: 60 |
| T3D1734 | Indium(III) bromide 13465-09-3 | Br3In 354.530 g/mol |  |
| Bromine is a powerful oxidizing agent and is able to release oxygen free radicals from the water in mucous membranes. These free radicals are also potent oxidizers and...more Number of Targets: 6 |
| T3D1746 | Platinum(II) bromide 13455-12-4 | Br2Pt 354.892 g/mol |  |
| Bromine is a powerful oxidizing agent and is able to release oxygen free radicals from the water in mucous membranes. These free radicals are also potent oxidizers and...more Number of Targets: 6 |
| T3D1581 | Ammonium hexachloro-palladate(IV) 7440-05-3 | Cl6H8N2Pd 355.210 g/mol |  |
| Due to their ability to form strong complexes with both inorganic and organic ligands, palladium ions can disturb cellular equilibria, replace other essential ions, an...more Number of Targets: 6 |
| T3D1160 | Ammonium diuranate 7783-22-4 | H10N2O5U 356.119 g/mol |  |
| Uranium is combined with either bicarbonate or a plasma protein in the blood but once in the kidney, it is released and forms complexes with phosphate ligands and prot...more Number of Targets: 1 |
| T3D2092 | 1,2,3,4,7-Pentachlorodibenzo-p-dioxin 39227-61-7 | C12H3Cl5O2 356.416 g/mol |  |
| CDDs cause their toxic effects by binding to the aryl hydrocarbon receptor and subsequently altering the trascription of certain genes. The affinity for the Ah recepto...more Number of Targets: 4 |
| T3D2093 | 1,2,3,7,8-Pentachlorodibenzo-p-dioxin 40321-76-4 | C12H3Cl5O2 356.416 g/mol |  |
| CDDs cause their toxic effects by binding to the aryl hydrocarbon receptor and subsequently altering the transcription of certain genes. The affinity for the Ah recept...more Number of Targets: 3 |
| T3D2094 | 1,2,4,7,8-Pentachlorodibenzo-p-dioxin 58802-08-7 | C12H3Cl5O2 356.416 g/mol |  |
| CDDs cause their toxic effects by binding to the aryl hydrocarbon receptor and subsequently altering the transcription of certain genes. The affinity for the Ah recept...more Number of Targets: 3 |
| T3D2095 | 1,2,3,8,9-Pentachlorodibenzo-p-dioxin 71925-18-3 | C12H3Cl5O2 356.416 g/mol |  |
| CDDs cause their toxic effects by binding to the aryl hydrocarbon receptor and subsequently altering the transcription of certain genes. The affinity for the Ah recept...more Number of Targets: 3 |