Browsing Toxins By Category
Displaying toxin 3051 - 3075 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D2038 | Tribromobiphenyl Ether 49690-94-0 | C12H7Br3O 406.895 g/mol |  |
| Like other halogenated aromatic hydrocarbons, polybrominated diphenyl ethers bind to the cellular aryl hydrocarbon receptor (AhR), which regulates the synthesis of a v...more Number of Targets: 6 |
| T3D0067 | beta Endosulfan 33213-65-9 | C9H6Cl6O3S 406.925 g/mol |  |
| Endosulfan antagonizes the action of the neurotransmitter gamma-aminobutyric acid (GABA) acting at the GABA-A receptors, effectively blocking the GABA-induced uptake o...more Number of Targets: 49 |
| T3D2905 | Trifluoperazine 117-89-5 | C21H24F3N3S 407.496 g/mol |  |
| Trifluoperazine blocks postsynaptic mesolimbic dopaminergic D1 and D2 receptors in the brain; depresses the release of hypothalamic and hypophyseal hormones and is bel...more Number of Targets: 18 |
| T3D1699 | Chlorfenapyr 122453-73-0 | C15H11BrClF3N2O 407.613 g/mol |  |
| Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary mechanism of toxicity for organic nitriles is their production of toxi...more Number of Targets: 45 |
| T3D1505 | Aluminium iodide 7784-23-8 | AlI3 407.695 g/mol |  |
| The main target organs of aluminum are the central nervous system and bone. Aluminum binds with dietary phosphorus and impairs gastrointestinal absorption of phosphoru...more Number of Targets: 3 |
| T3D4546 | Trifloxystrobin 141517-21-7 | C20H19F3N2O4 408.371 g/mol |  |
| Not Available Number of Targets: 27 |
| T3D3715 | Triacetoxyscirpenol 4297-61-4 | C21H28O8 408.442 g/mol |  |
| Unlike many other mycotoxins, trichothecenes do not require metabolic activation to exert their biological activity, instead directly reacting with cellular components...more Number of Targets: 2 |
| T3D4343 | Cholic acid 81-25-4 | C24H40O5 408.571 g/mol |  |
| Not Available Number of Targets: 22 |
| T3D3844 | Flufenpyr-ethyl 188489-07-8 | C16H13ClF4N2O4 408.732 g/mol |  |
| 'EP A does not have, at this time, available data to determine whether flufenpyr-ethyl has a common mechanism of toxicity with other substances.' (L2089) Number of Targets: 9 |
| T3D2136 | 1,2,3,4,6,7,9-Heptachlorodibenzofuran 70648-25-8 | C12HCl7O 409.307 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2139 | 1,2,3,4,6,8,9-Heptachlorodibenzofuran 69698-58-4 | C12HCl7O 409.307 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2144 | 1,2,3,4,7,8,9-Heptachlorodibenzofuran 55673-89-7 | C12HCl7O 409.307 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D0166 | 1,2,3,4,6,7,8-Heptachlorodibenzofuran 38998-75-3 | C12HCl7O 409.307 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D4084 | Veratramine 60-70-8 | C27H39NO2 409.604 g/mol |  |
| Veratramine produces a characteristic excitatory action on the central nervous system, producing both tremor and a characteristic "struggling" behavior. This behaviora...more Number of Targets: 0 |
| T3D0020 | Chlordane 57-74-9 | C10H6Cl8 409.779 g/mol |  |
| Chlordane is believed to bind irreversibly to DNA, leading to cell death or altered cellular function. It also affects transcription by antagonizing estrogen-related r...more Number of Targets: 54 |
| T3D0059 | cis-Chlordane 5103-71-9 | C10H6Cl8 409.779 g/mol |  |
| Chlordane is believed to bind irreversibly to DNA, leading to cell death or altered cellular function. It also affects transcription by antagonizing estrogen-related r...more Number of Targets: 14 |
| T3D0064 | trans-Chlordane 5103-74-2 | C10H6Cl8 409.779 g/mol |  |
| Chlordane is believed to bind irreversibly to DNA, leading to cell death or altered cellular function. It also affects transcription by antagonizing estrogen-related r...more Number of Targets: 14 |
| T3D0681 | Sodium cobaltinitrite 13600-98-1 | CoH6N6Na3O12 409.983 g/mol |  |
| Cobalt is believed to exhibit its toxicity through a oxidant-based and free radical-based processes. It produces oxygen radicals and may be oxidized to ionic cobalt, c...more Number of Targets: 44 |
| T3D4478 | Bensulfuron-methyl 83055-99-6 | C16H18N4O7S 410.402 g/mol |  |
| Not Available Number of Targets: 8 |
| T3D4501 | Ethametsulfuron methyl 97780-06-8 | C15H18N6O6S 410.405 g/mol |  |
| Not Available Number of Targets: 5 |
| T3D3492 | Cephalosporin 97519-39-6 | C15H14N4O6S2 410.425 g/mol |  |
| Ceftibuten exerts its bactericidal action by binding to essential target proteins of the bacterial cell wall. This binding leads to inhibition of cell-wall synthesis. Number of Targets: 1 |
| T3D2871 | Risperidone 106266-06-2 | C23H27FN4O2 410.485 g/mol |  |
| Blockade of dopaminergic D2 receptors in the limbic system alleviates positive symptoms of schizophrenia such as hallucinations, delusions, and erratic behavior and sp...more Number of Targets: 32 |
| T3D4827 | Forskolin 64657-11-0 and 66575-29-9 | C22H34O7 410.501 g/mol |  |
| Not Available Number of Targets: 17 |
| T3D0927 | Benfuracarb 82560-54-1 | C20H30N2O5S 410.528 g/mol |  |
| Benfuracarb is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylation of the active site...more Number of Targets: 2 |
| T3D4536 | Spirodiclofen 148477-71-8 | C21H24Cl2O4 411.319 g/mol |  |
| Not Available Number of Targets: 19 |