Browsing Toxins By Category
Displaying toxin 1826 - 1850 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D1149 | Manganese triacetate 19513-05-4 | C6H13MnO8 268.101 g/mol |  |
| Manganese is a cellular toxicant that can impair transport systems, enzyme activities, and receptor functions. It primarily targets the central nervous system, particu...more Number of Targets: 5 |
| T3D2822 | Pentostatin 53910-25-1 | C11H16N4O4 268.269 g/mol |  |
| Pentostatin is a potent transition state inhibitor of adenosine deaminase (ADA), the greatest activity of which is found in cells of the lymphoid system. T-cells have ...more Number of Targets: 1 |
| T3D2771 | Dexrazoxane 24584-09-6 | C11H16N4O4 268.269 g/mol |  |
| The mechanism by which dexrazoxane exerts its cardioprotective activity is not fully understood. Dexrazoxane is a cyclic derivative of EDTA that readily penetrates cel...more Number of Targets: 2 |
| T3D0996 | Potassium asulam 14089-43-1 | C8H9KN2O4S 268.331 g/mol |  |
| Some thiocarbamates (EPTC, Molinate, Pebulate, and Cycloate) share a common mechanism of toxicity, i.e. the inhibition of acetylcholinesterase. An acetylcholinesterase...more Number of Targets: 2 |
| T3D4693 | Equilin 474-86-2 | C18H20O2 268.350 g/mol |  |
| Estrogens enter the cells of responsive tissues (e.g., female organs, breasts, hypothalamus, pituitary) where they interact with a protein receptor, subsequently incre...more Number of Targets: 6 |
| T3D4744 | Diethylstilbestrol 56-53-1 | C18H20O2 268.350 g/mol |  |
| Estrogens diffuse into their target cells and interact with a protein receptor, the estrogen receptor. Target cells include the female reproductive tract, the mammary ...more Number of Targets: 9 |
| T3D1084 | 1-[(6-Chloropyridin-3-yl)methyl]-2-(nitromethylidene)-1,3-diazinane 72126-78-4 | C11H13ClN4O2 268.700 g/mol |  |
| Acts as a neurotransmitter mimic , having both excitatory and depressant effects, eventually blocking postsynaptic nicotinic receptors. (T10) Number of Targets: 7 |
| T3D3004 | Moclobemide 71320-77-9 | C13H17ClN2O2 268.739 g/mol |  |
| The mechanism of action of moclobemide involves the selective, reversible inhibition of MAO-A. This inhibition leads to a decrease in the metabolism and destruction of...more Number of Targets: 1 |
| T3D2940 | Rizatriptan 145202-66-0 | C15H19N5 269.345 g/mol |  |
| Three distinct pharmacological actions have been implicated in the antimigraine effect of the triptans: (1) stimulation of presynaptic 5-HT1D receptors, which serves t...more Number of Targets: 7 |
| T3D3005 | Orphenadrine 83-98-7 | C18H23NO 269.381 g/mol |  |
| Orphenadrine binds and inhibits both histamine H1 receptors and NMDA receptors. It restores the motor disturbances induced by neuroleptics, in particular the hyperkine...more Number of Targets: 16 |
| T3D0810 | Alachlor 15972-60-8 | C14H20ClNO2 269.767 g/mol |  |
| Its mode of action is elongase inhibition, and inhibition of geranylgeranyl pyrophosphate (GGPP) cyclisation enzymes. It is also know to inhibit biosynthesis of fatty...more Number of Targets: 26 |
| T3D0811 | Acetochlor 34256-82-1 | C14H20ClNO2 269.767 g/mol |  |
| Its mode of action is elongase inhibition, and inhibition of geranylgeranyl pyrophosphate (GGPP) cyclisation enzymes (L920). Number of Targets: 23 |
| T3D1163 | Uranium dioxide 1344-57-6 | O2U 270.028 g/mol |  |
| Uranium is combined with either bicarbonate or a plasma protein in the blood but once in the kidney, it is released and forms complexes with phosphate ligands and prot...more Number of Targets: 1 |
| T3D0956 | Di-allate 2303-16-4 | C10H17Cl2NOS 270.219 g/mol |  |
| The metabolic products of triallate, diallate and sulfallate appear to be mutagenic or carcinogenic. In particular, the 2-chloro-allyl group is responsible for the mu...more Number of Targets: 3 |
| T3D4888 | Apigenin 520-36-5 | C15H10O5 270.237 g/mol |  |
| Not Available Number of Targets: 9 |
| T3D3755 | Emodin 518-82-1 | C15H10O5 270.237 g/mol |  |
| Emodin is moderately cytotoxic and can inhibit the growth of many cell types by interfering with the cell cycle, possibly by stimulating the expression of p53 and p21....more Number of Targets: 20 |
| T3D0821 | Heratomin 61265-06-3 | C16H14O4 270.280 g/mol |  |
| The mechanism of action many furocoumarins is based on their ability to form photoadducts with DNA and other cellular components such as RNA, proteins, and several pro...more Number of Targets: 3 |
| T3D0831 | Isoimperatorin 482-45-1 | C16H14O4 270.280 g/mol |  |
| Isoimperatorin is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholin...more Number of Targets: 4 |
| T3D0838 | Imperatorin 482-44-0 | C16H14O4 270.280 g/mol |  |
| Imperatorin is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinest...more Number of Targets: 5 |
| T3D4025 | Hypoglycin B 502-37-4 | C12H18N2O5 270.282 g/mol |  |
| Generally, hypoglycin is an amino acid and chemically related to lysine. It competitively binds to enzymes used in the catabolism of lysine and is the reason why it an...more Number of Targets: 0 |
| T3D4933 | 4-tert-Butylphenyl salicylate 87-18-3 | C17H18O3 270.323 g/mol |  |
| Not Available Number of Targets: 2 |
| T3D4740 | Hexestrol 84-16-2 | C18H22O2 270.366 g/mol |  |
| Not Available Number of Targets: 16 |
| T3D4746 | Estrone 53-16-7 | C18H22O2 270.366 g/mol |  |
| Estrogens enter the cells of responsive tissues (e.g. female organs, breasts, hypothalamus, pituitary) where they interact with estrogen receptors. Hormone-bound estro...more Number of Targets: 5 |
| T3D4551 | Doxylamine 469-21-6 | C17H22N2O 270.369 g/mol |  |
| Like other antihistamines, doxylamine acts by competitively inhibiting histamine at H1 receptors. It also has substantial sedative and anticholinergic effects. Number of Targets: 3 |
| T3D1745 | Phosphorus tribromide 7789-60-8 | Br3P 270.686 g/mol |  |
| Bromine is a powerful oxidizing agent and is able to release oxygen free radicals from the water in mucous membranes. These free radicals are also potent oxidizers and...more Number of Targets: 6 |