Browsing Toxins By Category
Displaying toxin 2126 - 2150 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D3089 | Tutin 2571-22-4 | C15H18O6 294.300 g/mol |  |
| Tutin is a potent antagonist of the glycine receptor. (L1250) Number of Targets: 5 |
| T3D2896 | Proparacaine 499-67-2 | C16H26N2O3 294.389 g/mol |  |
| The exact mechanism whereby proparacaine and other local anesthetics influence the permeability of the cell membrane is unknown; however, several studies indicate that...more Number of Targets: 2 |
| T3D2870 | Trimipramine 739-71-9 | C20H26N2 294.434 g/mol |  |
| Trimipramine's mechanism of action differs from other tricyclic antidepressants. Trimipramine acts by decreasing the reuptake of norepinephrine and serotonin (5-HT). Number of Targets: 17 |
| T3D4742 | Sodium Tetradecyl Sulfate 1191-50-0 | C14H30O4S 294.451 g/mol |  |
| Sodium tetradecyl sulfate is a potent toxin for endothelial cells in that brief exposure to even low concentrations are effective in stripping endothelium over a consi...more Number of Targets: 18 |
| T3D4902 | Methyl linoleate 112-63-0 | C19H34O2 294.472 g/mol |  |
| Not Available Number of Targets: 4 |
| T3D1836 | Silver(I) selenide 1302-09-6 | Ag2Se 294.700 g/mol |  |
| Selenium readily substitutes for sulfur in biomolecules and in many biochemical reactions, especially when the concentration of selenium is high and the concentration ...more Number of Targets: 17 |
| T3D3023 | Estazolam 29975-16-4 | C16H11ClN4 294.738 g/mol |  |
| Benzodiazepines bind nonspecifically to benzodiazepine receptors, which affects affects muscle relaxation, anticonvulsant activity, motor coordination, and memory. As ...more Number of Targets: 18 |
| T3D1323 | Lead oxalate 814-93-7 | C2O4Pb 295.200 g/mol |  |
| Lead mimics other biologically important metals, such as zinc, calcium, and iron, competing as cofactors for many of their respective enzymatic reactions. For example,...more Number of Targets: 29 |
| T3D4618 | Prunasin 99-18-3 | C14H17NO6 295.288 g/mol |  |
| Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary mechanism of toxicity for organic nitriles is their production of toxi...more Number of Targets: 0 |
| T3D4619 | Sambunigrin 99-19-4 | C14H17NO6 295.288 g/mol |  |
| Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary mechanism of toxicity for organic nitriles is their production of toxi...more Number of Targets: 0 |
| T3D4650 | Nimetazepam 2011-67-8 | C16H13N3O3 295.293 g/mol |  |
| Benzodiazepines bind nonspecifically to benzodiazepine receptors BNZ1, which mediates sleep, and BNZ2, which affects affects muscle relaxation, anticonvulsant activity...more Number of Targets: 18 |
| T3D4480 | Butralin 33629-47-9 | C14H21N3O4 295.334 g/mol |  |
| Not Available Number of Targets: 14 |
| T3D4534 | Quintozene 82-68-8 | C6Cl5NO2 295.335 g/mol |  |
| Not Available Number of Targets: 11 |
| T3D1338 | Diethyldimethyl lead 1762-27-2 | C6H16Pb 295.400 g/mol |  |
| Lead mimics other biologically important metals, such as zinc, calcium, and iron, competing as cofactors for many of their respective enzymatic reactions. For example,...more Number of Targets: 29 |
| T3D2856 | Sumatriptan 103628-46-2 | C14H21N3O2S 295.400 g/mol |  |
| The 5-HT1B and 5-HT1D receptors function as autoreceptors, which inhibit the firing of serotonin neurons and a reduction in the synthesis and release of serotonin upon...more Number of Targets: 14 |
| T3D1736 | Iron(III) bromide 10031-26-2 | Br3Fe 295.557 g/mol |  |
| Bromine is a powerful oxidizing agent and is able to release oxygen free radicals from the water in mucous membranes. These free radicals are also potent oxidizers and...more Number of Targets: 6 |
| T3D4544 | Triadimenol 55219-65-3 | C14H18ClN3O2 295.765 g/mol |  |
| Not Available Number of Targets: 24 |
| T3D0314 | Tryparsamide 554-72-3 | C8H10AsN2NaO4 296.087 g/mol |  |
| Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co...more Number of Targets: 44 |
| T3D4729 | Diclofenac 15307-86-5 | C14H11Cl2NO2 296.149 g/mol |  |
| The antiinflammatory effects of diclofenac are believed to be due to inhibition of both leukocyte migration and the enzyme cylooxygenase (COX-1 and COX-2), leading to ...more Number of Targets: 8 |
| T3D1672 | 3,3'-Dimethoxybenzidine-4,4'-diisocyanate 91-93-0 | C16H12N2O4 296.278 g/mol |  |
| Cyanide is an inhibitor of cytochrome c oxidase in the fourth complex of the electron transport chain (found in the membrane of the mitochondria of eukaryotic cells). ...more Number of Targets: 39 |
| T3D3668 | Deoxynivalenol 51481-10-8 | C15H20O6 296.316 g/mol |  |
| Unlike many other mycotoxins, trichothecenes do not require metabolic activation to exert their biological activity, instead directly reacting with cellular components...more Number of Targets: 2 |
| T3D4743 | Ethinyl Estradiol 57-63-6 | C20H24O2 296.403 g/mol |  |
| Estrogens diffuse into their target cells and interact with a protein receptor. Target cells include the female reproductive tract, the mammary gland, the hypothalamus...more Number of Targets: 17 |
| T3D2924 | Methdilazine 1982-37-2 | C18H20N2S 296.430 g/mol |  |
| Methdilazine binds to the histamine H1 receptor. This blocks the action of endogenous histamine, which subsequently leads to temporary relief of the negative symptoms ...more Number of Targets: 1 |
| T3D2557 | Disulfiram 97-77-8 | C10H20N2S4 296.539 g/mol |  |
| Disulfiram blocks the oxidation of alcohol at the acetaldehyde stage during alcohol metabolism following disulfiram intake causing an accumulation of acetaldehyde in t...more Number of Targets: 24 |
| T3D3853 | Folpet 133-07-3 | C9H4Cl3NO2S 296.558 g/mol |  |
| Not Available Number of Targets: 8 |