Browsing Toxins
Displaying toxin 876 - 900 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D1648 | Palladium(II) cyanide 2035-66-7 | C2N2Pd 158.450 g/mol |  |
| Cyanide is an inhibitor of cytochrome c oxidase in the fourth complex of the electron transport chain (found in the membrane of the mitochondria of eukaryotic cells). ...more Number of Targets: 48 |
| T3D1576 | Palladium(II) chloride 7647-10-1 | Cl2Pd 177.330 g/mol |  |
| Due to their ability to form strong complexes with both inorganic and organic ligands, palladium ions can disturb cellular equilibria, replace other essential ions, an...more Number of Targets: 6 |
| T3D1575 | Palladium(II) acetate 3375-31-3 | C4H6O4Pd 224.510 g/mol |  |
| Due to their ability to form strong complexes with both inorganic and organic ligands, palladium ions can disturb cellular equilibria, replace other essential ions, an...more Number of Targets: 6 |
| T3D1574 | Palladium hydride 12648-42-9 | H2Pd 108.440 g/mol |  |
| Due to their ability to form strong complexes with both inorganic and organic ligands, palladium ions can disturb cellular equilibria, replace other essential ions, an...more Number of Targets: 6 |
| T3D1573 | Palladium acetylacetonate 24-61-4 | C10H14O4Pd 304.640 g/mol |  |
| Due to their ability to form strong complexes with both inorganic and organic ligands, palladium ions can disturb cellular equilibria, replace other essential ions, an...more Number of Targets: 6 |
| T3D0180 | Palladium 7440-05-03 | Pd 106.420 g/mol |  |
| Palladium ions are able to inhibit most major cellular fuctions. They form strong complexes with both inorganic and organic ligands, substitute essential ions, bind to...more Number of Targets: 5 |
| T3D3897 | Paclobutrazol 76738-62-0 | C15H20ClN3O 293.792 g/mol |  |
| Not Available Number of Targets: 18 |
| T3D4019 | Paclitaxel 33069-62-4 | C47H51NO14 853.906 g/mol |  |
| Paclitaxel interferes with the normal function of microtubule growth. Whereas drugs like colchicine cause the depolymerization of microtubules in vivo, paclitaxel arre...more Number of Targets: 6 |
| T3D1808 | p-Xylyl bromide 28258-59-5 | C8H9Br 185.061 g/mol |  |
| Organobromide compounds such as p-Xylyl bromide are strong alkylating agents. Consequently they can readily modify free thiols (cysteines) and methionine residues of ...more Number of Targets: 1 |
| T3D0185 | p-Xylene 106-42-3 | C8H10 106.165 g/mol |  |
| p-Xylene is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinestera...more Number of Targets: 4 |
| T3D4882 | p-Cymene 99-87-6 | C10H14 134.218 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D4184 | p-Cresol sulfate 3233-58-7 | C7H8O4S 188.201 g/mol |  |
| Uremic toxins such as p-Cresol sulfate are actively transported into the kidneys via organic ion transporters (especially OAT3). Increased levels of uremic toxins can ...more Number of Targets: 3 |
| T3D0170 | p-Cresol 106-44-5 | C7H8O 108.138 g/mol |  |
| p-Cresol is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinestera...more Number of Targets: 5 |
| T3D4657 | P-Chlorobenzylidenemalonitrile 1867-38-5 | C10H5ClN2 188.613 g/mol |  |
| Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary mechanism of toxicity for organic nitriles is their production of toxi...more Number of Targets: 1 |
| T3D4656 | P-Chloroacetophenone 99-91-2 | C8H7ClO 154.594 g/mol |  |
| Not Available Number of Targets: 2 |
| T3D1303 | p-Azobenzenearsonate 7334-23-8 | C12H12As2N2O6 430.077 g/mol |  |
| Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co...more Number of Targets: 44 |
| T3D4986 | p-Anisidine 104-94-9 | C7H9NO 123.153 g/mol |  |
| p-Anisidine reacts with secondary oxidation products such as aldehydes and ketones in fats and oils. (Wikipedia) Number of Targets: 0 |
| T3D0021 | P,P'-DDE 72-55-9 | C14H8Cl4 318.025 g/mol |  |
| DDE toxicity occurs via at least four mechanisms, possibly all functioning simultaneously. DDE reduces potassium transport across the membrane. DDE inhibits the inacti...more Number of Targets: 60 |
| T3D0025 | P,P'-DDD 72-54-8 | C14H10Cl4 320.041 g/mol |  |
| DDD toxicity occurs via at least four mechanisms, possibly all functioning simultaneously. DDD reduces potassium transport across the membrane. DDD inhibits the inacti...more Number of Targets: 62 |
| T3D4725 | Ozone 10028-15-6 | O3 47.998 g/mol |  |
| Ozone is a strong oxidant and reacts directly with organic double bonds. When ozone breaks down to dioxygen it gives rise to oxygen free radicals, which are highly rea...more Number of Targets: 1 |
| T3D3953 | Oxytetracycline 79-57-2 | C22H24N2O9 460.434 g/mol |  |
| Tetracyclines target the 28S small subunit of the mitochondrial ribosome thereby deactivation mitochondrial protein synthesis. As a result tetracyclines are cytotoxic ...more Number of Targets: 12 |
| T3D3015 | Oxymorphone 76-41-5 | C17H19NO4 301.337 g/mol |  |
| Oxymorphone interacts predominantly with the opioid mu-receptor. These mu-binding sites are discretely distributed in the human brain, with high densities in the poste...more Number of Targets: 3 |
| T3D3896 | Oxyfluorfen 42874-03-3 | C15H11ClF3NO4 361.700 g/mol |  |
| Not Available Number of Targets: 14 |
| T3D2809 | Oxycodone 76-42-6 | C18H21NO4 315.364 g/mol |  |
| Oxycodone acts as a weak agonist at mu, kappa, and delta opioid receptors within the central nervous system (CNS). Oxycodone primarily affects mu-type opioid receptors...more Number of Targets: 5 |
| T3D4807 | Oxybenzone 131-57-7 | C14H12O3 228.243 g/mol |  |
| Oxybenzone absorbs UV-A ultraviolet rays, preventing them from reaching the skin. Number of Targets: 5 |