Browsing Toxins
Displaying toxin 1551 - 1575 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D2870 | Trimipramine 739-71-9 | C20H26N2 294.434 g/mol |  |
| Trimipramine's mechanism of action differs from other tricyclic antidepressants. Trimipramine acts by decreasing the reuptake of norepinephrine and serotonin (5-HT). Number of Targets: 17 |
| T3D2896 | Proparacaine 499-67-2 | C16H26N2O3 294.389 g/mol |  |
| The exact mechanism whereby proparacaine and other local anesthetics influence the permeability of the cell membrane is unknown; however, several studies indicate that...more Number of Targets: 2 |
| T3D3089 | Tutin 2571-22-4 | C15H18O6 294.300 g/mol |  |
| Tutin is a potent antagonist of the glycine receptor. (L1250) Number of Targets: 5 |
| T3D1594 | Sodium tetrachloro-palladate(II) 13820-53-6 | Cl4Na2Pd 294.210 g/mol |  |
| Due to their ability to form strong complexes with both inorganic and organic ligands, palladium ions can disturb cellular equilibria, replace other essential ions, an...more Number of Targets: 6 |
| T3D1497 | Aluminium lactate 7784-18-1 | C9H15AlO9 294.192 g/mol |  |
| The main target organs of aluminum are the central nervous system and bone. Aluminum binds with dietary phosphorus and impairs gastrointestinal absorption of phosphoru...more Number of Targets: 3 |
| T3D0706 | Potassium dichromate 7778-50-9 | Cr2K2O7 294.185 g/mol |  |
| Hexavalent chromium's carcinogenic effects are caused by its metabolites, pentavalent and trivalent chromium. The DNA damage may be caused by hydroxyl radicals produce...more Number of Targets: 5 |
| T3D3897 | Paclobutrazol 76738-62-0 | C15H20ClN3O 293.792 g/mol |  |
| Not Available Number of Targets: 18 |
| T3D4543 | Triadimefon 43121-43-3 | C14H16ClN3O2 293.749 g/mol |  |
| Not Available Number of Targets: 14 |
| T3D3792 | Amitraz 33089-61-1 | C19H23N3 293.406 g/mol |  |
| The pharmacological activity of amitraz includes different mechanisms of action leading to toxic effects in humans as well as in animals. Many of these effects and mos...more Number of Targets: 8 |
| T3D3624 | Sodium lauroyl sarcosinate 137-16-6 | C15H28NNaO3 293.378 g/mol |  |
| While acyl sarcosines themselves are not toxic, they are nitrosating agents. Nitrosating agents may decompose and/or react to cause nitrosamine contamination. Nitrosam...more Number of Targets: 2 |
| T3D4796 | Anastrozole 120511-73-1 | C17H19N5 293.366 g/mol |  |
| Anastrozole selectively inhibits aromatase. The principal source of circulating estrogen (primarily estradiol) is conversion of adrenally-generated androstenedione to ...more Number of Targets: 2 |
| T3D2925 | Ondansetron 99614-02-5 | C18H19N3O 293.363 g/mol |  |
| Ondansetron is a selective serotonin 5-HT3 receptor antagonist. The antiemetic activity of the drug is brought about through the inhibition of 5-HT3 receptors present ...more Number of Targets: 15 |
| T3D0953 | Debacarb 62732-91-6 | C14H19N3O4 293.318 g/mol |  |
| Debacarb is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylation of the active sites o...more Number of Targets: 2 |
| T3D3716 | Trichodermin 4682-50-2 | C17H24O4 292.370 g/mol |  |
| Unlike many other mycotoxins, trichothecenes do not require metabolic activation to exert their biological activity, instead directly reacting with cellular components...more Number of Targets: 2 |
| T3D1236 | Tin(II) fluoroborate 13814-97-6 | B2F8Sn 292.320 g/mol |  |
| Inorganic and organic tin compounds are weak inhibitors of alcohol dehydrogenase. (A183) Number of Targets: 7 |
| T3D4977 | Edetic Acid 62-33-9 | C10H16N2O8 292.243 g/mol |  |
| The pharmacologic effects of edetate calcium disodium are due to the formation of chelates with divalent and trivalent metals. A stable chelate will form with any meta...more Number of Targets: 3 |
| T3D4993 | 2-hydroxyflutamide 52806-53-8 | C11H11F3N2O4 292.211 g/mol |  |
| Hydroxyflutamide is an antiandrogen. Antiandrogens alter the androgen pathway by blocking the appropriate receptors, competing for binding sites on the cell's surface,...more Number of Targets: 0 |
| T3D3487 | Brimonidine 59803-98-4 | C11H10BrN5 292.135 g/mol |  |
| Brimonidine is an alpha adrenergic receptor agonist (primarily alpha-2). It has a peak ocular hypotensive effect occurring at two hours post-dosing. Fluorophotometric ...more Number of Targets: 3 |
| T3D0027 | Aroclor 1248 12672-29-6 | C12H6Cl4 291.988 g/mol |  |
| The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcriptio...more Number of Targets: 7 |
| T3D0429 | 2,2',3,3'-Tetrachlorobiphenyl 38444-93-8 | C12H6Cl4 291.988 g/mol |  |
| The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcriptio...more Number of Targets: 7 |
| T3D0430 | 2,2',3,4-Tetrachlorobiphenyl 52663-59-9 | C12H6Cl4 291.988 g/mol |  |
| The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcriptio...more Number of Targets: 7 |
| T3D0431 | 2,2',3,4'-Tetrachlorobiphenyl 36559-22-5 | C12H6Cl4 291.988 g/mol |  |
| The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcriptio...more Number of Targets: 7 |
| T3D0432 | 2,2',3,5-Tetrachlorobiphenyl 70362-46-8 | C12H6Cl4 291.988 g/mol |  |
| The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcriptio...more Number of Targets: 7 |
| T3D0433 | 2,2',3,5'-Tetrachlorobiphenyl 41464-39-5 | C12H6Cl4 291.988 g/mol |  |
| The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcriptio...more Number of Targets: 7 |
| T3D0434 | 2,2',3,6-Tetrachlorobiphenyl 70362-45-7 | C12H6Cl4 291.988 g/mol |  |
| The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcriptio...more Number of Targets: 7 |