Displaying toxin 2526 - 2550 of 3678 in total
T3DB ID Name
CAS Number
Formula
Weight
StructureTypeMechanism of Toxicity
T3D4022Sanguinarine
2447-54-3
C20H14NO4
332.329 g/mol
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  • Food Toxin
  • Metabolite
  • Natural Compound
  • Organic Compound
  • Plant Toxin
Sanguinarine, at micromolar concentrations, imparts cell growth inhibitory response in human squamous carcinoma (A431) cells via an induction of apoptosis. This is whi...more
Number of Targets: 0
T3D3702Crotocin
21284-11-7
C19H24O5
332.391 g/mol
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  • Ester
  • Ether
  • Fungal Toxin
  • Lachrymator
  • Mycotoxin
  • Natural Compound
  • Organic Compound
Unlike many other mycotoxins, trichothecenes do not require metabolic activation to exert their biological activity, instead directly reacting with cellular components...more
Number of Targets: 2
T3D3718Trichothecin
6379-69-7
C19H24O5
332.391 g/mol
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  • Ester
  • Ether
  • Fungal Toxin
  • Lachrymator
  • Mycotoxin
  • Natural Compound
  • Organic Compound
Unlike many other mycotoxins, trichothecenes do not require metabolic activation to exert their biological activity, instead directly reacting with cellular components...more
Number of Targets: 2
T3D3867Isoxaben
82558-50-7
C18H24N2O4
332.394 g/mol
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  • Amide
  • Amine
  • Ester
  • Ether
  • Herbicide
  • Organic Compound
  • Pesticide
  • Synthetic Compound
Not Available
Number of Targets: 20
T3D3630Sodium laureth sulfate
9004-82-4
C14H29NaO5S
332.432 g/mol
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  • Cosmetic Toxin
  • Ester
  • Ether
  • Household Toxin
  • Lachrymator
  • Organic Compound
  • Synthetic Compound
While sodium laureth sulfate itself is not toxic, it is a nitrosating agent. Nitrosating agents may decompose and/or react to cause nitrosamine contamination. Nitrosam...more
Number of Targets: 3
T3D1168Uranium pentafluoride
10049-14-6
F5U
333.021 g/mol
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  • Fluoride Compound
  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Pollutant
  • Radioactive
  • Synthetic Compound
  • Uranium Compound
Uranium is combined with either bicarbonate or a plasma protein in the blood but once in the kidney, it is released and forms complexes with phosphate ligands and prot...more
Number of Targets: 1
T3D3832Ethalfluralin
55283-68-6
C13H14F3N3O4
333.263 g/mol
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  • Amine
  • Food Toxin
  • Herbicide
  • Lachrymator
  • Organic Compound
  • Organofluoride
  • Synthetic Compound
Not Available
Number of Targets: 13
T3D3926Tebufenpyrad
119168-77-3
C18H24ClN3O
333.856 g/mol
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  • Amide
  • Amine
  • Ester
  • Insecticide
  • Organic Compound
  • Organochloride
  • Pesticide
  • Synthetic Compound
Not Available
Number of Targets: 40
T3D3030Bromodiphenhydramine
118-23-0
C17H20BrNO
334.251 g/mol
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  • Amine
  • Bromide Compound
  • Drug
  • Ether
  • Histamine Antagonist
  • Metabolite
  • Organic Compound
  • Organobromide
  • Synthetic Compound
Bromodiphenhydramine competes with free histamine for binding at HA-receptor sites. This antagonizes the effects of histamine on HA-receptors, leading to a reduction o...more
Number of Targets: 1
T3D2743Mitomycin
50-07-7
C15H18N4O5
334.327 g/mol
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  • Alkylating Agent
  • Amide
  • Amine
  • Antibiotic, Antineoplastic
  • Cross-Linking Reagent
  • Drug
  • Ester
  • Ether
  • Metabolite
  • Nucleic Acid Synthesis Inhibitor
  • Organic Compound
  • Synthetic Compound
Mitomycin is activated in vivo to a bifunctional and trifunctional alkylating agent. Binding to DNA leads to cross-linking and inhibition of DNA synthesis and function...more
Number of Targets: 1
T3D3086Strychnine
57-24-9
C21H22N2O2
334.412 g/mol
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  • Amide
  • Amine
  • Ether
  • Natural Compound
  • Organic Compound
  • Pesticide
  • Plant Toxin
Strychnine acts as an antagonist at the inhibitory or strychnine-sensitive glycine receptor, a ligand-gated chloride channel in the spinal cord and the brain. (L1230)
Number of Targets: 8
T3D3647Diisohexyl phthalate
146-50-9
C20H30O4
334.450 g/mol
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  • Aromatic Hydrocarbon
  • Cosmetic Toxin
  • Ester
  • Ether
  • Food Toxin
  • Household Toxin
  • Industrial/Workplace Toxin
  • Organic Compound
  • Phthalate
  • Plasticizer
  • Synthetic Compound
Phthalate esters are endocrine disruptors. They decrease foetal testis testosterone production and reduce the expression of steroidogenic genes by decreasing mRNA expr...more
Number of Targets: 0
T3D3653Di-n-hexyl phthalate
84-75-3
C20H30O4
334.450 g/mol
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  • Aromatic Hydrocarbon
  • Cosmetic Toxin
  • Ester
  • Ether
  • Food Toxin
  • Household Toxin
  • Industrial/Workplace Toxin
  • Organic Compound
  • Phthalate
  • Plasticizer
  • Synthetic Compound
Phthalate esters are endocrine disruptors. They decrease foetal testis testosterone production and reduce the expression of steroidogenic genes by decreasing mRNA expr...more
Number of Targets: 10
T3D4485Chlorpyrifos oxon
5598-15-2
C9H11Cl3NO4P
334.521 g/mol
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  • Ester
  • Organic Compound
  • Organochloride
  • Pesticide
  • Synthetic Compound
Chlorpyrifos oxon is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcho...more
Number of Targets: 22
T3D2908Progabide
62666-20-0
C17H16ClFN2O2
334.773 g/mol
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  • Amide
  • Amine
  • Anticonvulsant
  • Antidepressant
  • Antidepressive Agent
  • Antidyskinetic
  • Antiparkinson Agent
  • Drug
  • Ester
  • GABA Agonist
  • Ketone
  • Metabolite
  • Organic Compound
  • Organochloride
  • Organofluoride
  • Synthetic Compound
Progabide binds to both GABAA and GABAB receptors located on the terminals of primary afferent fibers. Binding to GABAA results in an increased affinity of the GABA re...more
Number of Targets: 2
T3D1326Lead telluride
1314-91-6
PbTe
334.800 g/mol
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  • Industrial/Workplace Toxin
  • Inorganic Compound
  • Lead Compound
  • Pollutant
  • Synthetic Compound
Lead mimics other biologically important metals, such as zinc, calcium, and iron, competing as cofactors for many of their respective enzymatic reactions. For example,...more
Number of Targets: 29
T3D4585Lormetazepam
848-75-9
C16H12Cl2N2O2
335.185 g/mol
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  • Amide
  • Amine
  • Drug
  • Food Toxin
  • Metabolite
  • Organic Compound
  • Organochloride
  • Synthetic Compound
Benzodiazepines bind nonspecifically to benzodiazepine receptors BNZ1, which mediates sleep, and BNZ2, which affects affects muscle relaxation, anticonvulsant activity...more
Number of Targets: 18
T3D3796Benfluralin
1861-40-1
C13H16F3N3O4
335.279 g/mol
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  • Amine
  • Herbicide
  • Organic Compound
  • Organofluoride
  • Pesticide
  • Synthetic Compound
Not Available
Number of Targets: 8
T3D4548Trifluralin
1582-09-8
C13H16F3N3O4
335.279 g/mol
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  • Amine
  • Herbicide
  • Household Toxin
  • Organic Compound
  • Organofluoride
  • Pesticide
  • Pollutant
  • Synthetic Compound
Not Available
Number of Targets: 10
T3D1461Zinc laurate
2452-01-9
C14H25NO8
335.350 g/mol
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  • Amine
  • Industrial/Workplace Toxin
  • Organic Compound
  • Organometallic
  • Synthetic Compound
  • Zinc Compound
Anaemia results from the excessive absorption of zinc suppressing copper and iron absorption, most likely through competitive binding of intestinal mucosal cells. Unba...more
Number of Targets: 1
T3D4059Senecionine
130-01-8
C18H25NO5
335.395 g/mol
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  • Amine
  • Ester
  • Ether
  • Natural Compound
  • Organic Compound
  • Plant Toxin
Senecionine is classified as a pyrrolizidine alkaloid (PA). Unsaturated pyrrolizidine alkaloids are hepatotoxic, that is, damaging to the liver. PAs also cause hepatic...more
Number of Targets: 0
T3D2931Almotriptan
181183-52-8
C17H25N3O2S
335.464 g/mol
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  • Amide
  • Amine
  • Anti-Inflammatory Agent
  • Anti-Migraine Agent
  • Drug
  • Metabolite
  • Organic Compound
  • Selective Serotonin Agonist
  • Serotonin Agonist
  • Serotonin Antagonist
  • Serotonin Receptor Agonist
  • Synthetic Compound
  • Vasoconstrictor Agent
Almotriptan binds with high affinity to human 5-HT1B and 5-HT1D receptors leading to cranial blood vessel constriction.
Number of Targets: 2
T3D2939Naratriptan
121679-13-8
C17H25N3O2S
335.464 g/mol
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  • Amide
  • Amine
  • Drug
  • Metabolite
  • Organic Compound
  • Selective Serotonin Agonist
  • Serotonin Agonist
  • Serotonin Antagonist
  • Serotonin Receptor Agonist
  • Synthetic Compound
  • Vasoconstrictor Agent
Three distinct pharmacological actions have been implicated in the antimigraine effect of the triptans: (1) stimulation of presynaptic 5-HT1D receptors, which serves t...more
Number of Targets: 4
T3D3512Hydroxychloroquine
118-42-3
C18H26ClN3O
335.872 g/mol
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  • Amine
  • Antimalarial
  • Antirheumatic Agent
  • Dermatologic Agent
  • Drug
  • Enzyme Inhibitor
  • Metabolite
  • Organic Compound
  • Organochloride
  • Synthetic Compound
Although the exact mechanism of action is unknown, it may be based on ability of hydroxychloroquine to bind to and alter DNA. Hydroxychloroquine has also has been foun...more
Number of Targets: 3
T3D4484Chlorethoxyfos
54593-83-8
C6H11Cl4O3PS
336.001 g/mol
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  • Ester
  • Insecticide
  • Organic Compound
  • Organochloride
  • Pesticide
  • Synthetic Compound
Chlorethoxyfos is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholin...more
Number of Targets: 7
Displaying toxin 2526 - 2550 of 3678 in total