
Browsing Toxins
Displaying toxin 2526 - 2550 of 3678 in total
T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
---|---|---|---|---|---|
T3D4022 | Sanguinarine 2447-54-3 | C20H14NO4 332.329 g/mol | ![]() |
| Sanguinarine, at micromolar concentrations, imparts cell growth inhibitory response in human squamous carcinoma (A431) cells via an induction of apoptosis. This is whi...more Number of Targets: 0 |
T3D3702 | Crotocin 21284-11-7 | C19H24O5 332.391 g/mol | ![]() |
| Unlike many other mycotoxins, trichothecenes do not require metabolic activation to exert their biological activity, instead directly reacting with cellular components...more Number of Targets: 2 |
T3D3718 | Trichothecin 6379-69-7 | C19H24O5 332.391 g/mol | ![]() |
| Unlike many other mycotoxins, trichothecenes do not require metabolic activation to exert their biological activity, instead directly reacting with cellular components...more Number of Targets: 2 |
T3D3867 | Isoxaben 82558-50-7 | C18H24N2O4 332.394 g/mol | ![]() |
| Not Available Number of Targets: 20 |
T3D3630 | Sodium laureth sulfate 9004-82-4 | C14H29NaO5S 332.432 g/mol | ![]() |
| While sodium laureth sulfate itself is not toxic, it is a nitrosating agent. Nitrosating agents may decompose and/or react to cause nitrosamine contamination. Nitrosam...more Number of Targets: 3 |
T3D1168 | Uranium pentafluoride 10049-14-6 | F5U 333.021 g/mol | ![]() |
| Uranium is combined with either bicarbonate or a plasma protein in the blood but once in the kidney, it is released and forms complexes with phosphate ligands and prot...more Number of Targets: 1 |
T3D3832 | Ethalfluralin 55283-68-6 | C13H14F3N3O4 333.263 g/mol | ![]() |
| Not Available Number of Targets: 13 |
T3D3926 | Tebufenpyrad 119168-77-3 | C18H24ClN3O 333.856 g/mol | ![]() |
| Not Available Number of Targets: 40 |
T3D3030 | Bromodiphenhydramine 118-23-0 | C17H20BrNO 334.251 g/mol | ![]() |
| Bromodiphenhydramine competes with free histamine for binding at HA-receptor sites. This antagonizes the effects of histamine on HA-receptors, leading to a reduction o...more Number of Targets: 1 |
T3D2743 | Mitomycin 50-07-7 | C15H18N4O5 334.327 g/mol | ![]() |
| Mitomycin is activated in vivo to a bifunctional and trifunctional alkylating agent. Binding to DNA leads to cross-linking and inhibition of DNA synthesis and function...more Number of Targets: 1 |
T3D3086 | Strychnine 57-24-9 | C21H22N2O2 334.412 g/mol | ![]() |
| Strychnine acts as an antagonist at the inhibitory or strychnine-sensitive glycine receptor, a ligand-gated chloride channel in the spinal cord and the brain. (L1230) Number of Targets: 8 |
T3D3647 | Diisohexyl phthalate 146-50-9 | C20H30O4 334.450 g/mol | ![]() |
| Phthalate esters are endocrine disruptors. They decrease foetal testis testosterone production and reduce the expression of steroidogenic genes by decreasing mRNA expr...more Number of Targets: 0 |
T3D3653 | Di-n-hexyl phthalate 84-75-3 | C20H30O4 334.450 g/mol | ![]() |
| Phthalate esters are endocrine disruptors. They decrease foetal testis testosterone production and reduce the expression of steroidogenic genes by decreasing mRNA expr...more Number of Targets: 10 |
T3D4485 | Chlorpyrifos oxon 5598-15-2 | C9H11Cl3NO4P 334.521 g/mol | ![]() |
| Chlorpyrifos oxon is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcho...more Number of Targets: 22 |
T3D2908 | Progabide 62666-20-0 | C17H16ClFN2O2 334.773 g/mol | ![]() |
| Progabide binds to both GABAA and GABAB receptors located on the terminals of primary afferent fibers. Binding to GABAA results in an increased affinity of the GABA re...more Number of Targets: 2 |
T3D1326 | Lead telluride 1314-91-6 | PbTe 334.800 g/mol | ![]() |
| Lead mimics other biologically important metals, such as zinc, calcium, and iron, competing as cofactors for many of their respective enzymatic reactions. For example,...more Number of Targets: 29 |
T3D4585 | Lormetazepam 848-75-9 | C16H12Cl2N2O2 335.185 g/mol | ![]() |
| Benzodiazepines bind nonspecifically to benzodiazepine receptors BNZ1, which mediates sleep, and BNZ2, which affects affects muscle relaxation, anticonvulsant activity...more Number of Targets: 18 |
T3D3796 | Benfluralin 1861-40-1 | C13H16F3N3O4 335.279 g/mol | ![]() |
| Not Available Number of Targets: 8 |
T3D4548 | Trifluralin 1582-09-8 | C13H16F3N3O4 335.279 g/mol | ![]() |
| Not Available Number of Targets: 10 |
T3D1461 | Zinc laurate 2452-01-9 | C14H25NO8 335.350 g/mol | ![]() |
| Anaemia results from the excessive absorption of zinc suppressing copper and iron absorption, most likely through competitive binding of intestinal mucosal cells. Unba...more Number of Targets: 1 |
T3D4059 | Senecionine 130-01-8 | C18H25NO5 335.395 g/mol | ![]() |
| Senecionine is classified as a pyrrolizidine alkaloid (PA). Unsaturated pyrrolizidine alkaloids are hepatotoxic, that is, damaging to the liver. PAs also cause hepatic...more Number of Targets: 0 |
T3D2931 | Almotriptan 181183-52-8 | C17H25N3O2S 335.464 g/mol | ![]() |
| Almotriptan binds with high affinity to human 5-HT1B and 5-HT1D receptors leading to cranial blood vessel constriction. Number of Targets: 2 |
T3D2939 | Naratriptan 121679-13-8 | C17H25N3O2S 335.464 g/mol | ![]() |
| Three distinct pharmacological actions have been implicated in the antimigraine effect of the triptans: (1) stimulation of presynaptic 5-HT1D receptors, which serves t...more Number of Targets: 4 |
T3D3512 | Hydroxychloroquine 118-42-3 | C18H26ClN3O 335.872 g/mol | ![]() |
| Although the exact mechanism of action is unknown, it may be based on ability of hydroxychloroquine to bind to and alter DNA. Hydroxychloroquine has also has been foun...more Number of Targets: 3 |
T3D4484 | Chlorethoxyfos 54593-83-8 | C6H11Cl4O3PS 336.001 g/mol | ![]() |
| Chlorethoxyfos is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholin...more Number of Targets: 7 |