Browsing Toxins
Displaying toxin 2601 - 2625 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D2195 | 1,3,4,6,8-Pentachlorodibenzofuran 83704-55-6 | C12H3Cl5O 340.417 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2196 | 1,3,4,6,9-Pentachlorodibenzofuran 70648-15-6 | C12H3Cl5O 340.417 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2198 | 1,3,4,7,8-Pentachlorodibenzofuran 58802-16-7 | C12H3Cl5O 340.417 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2199 | 1,3,4,7,9-Pentachlorodibenzofuran 70648-20-3 | C12H3Cl5O 340.417 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2203 | 2,3,4,7,9-Pentachlorodibenzofuran 70648-21-4 | C12H3Cl5O 340.417 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D0168 | 2,3,4,7,8-Pentachlorodibenzofuran 57117-31-4 | C12H3Cl5O 340.417 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2231 | 2,3,4,6,7-Pentachlorodibenzofuran 57117-43-8 | C12H3Cl5O 340.417 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2232 | 2,3,4,6,8-Pentachlorodibenzofuran 67481-22-5 | C12H3Cl5O 340.417 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D3526 | Pentamidine 100-33-4 | C19H24N4O2 340.420 g/mol |  |
| The mode of action of pentamidine is not fully understood. It is thought that the drug interferes with nuclear metabolism producing inhibition of the synthesis of DNA,...more Number of Targets: 11 |
| T3D2888 | Propiomazine 362-29-8 | C20H24N2OS 340.482 g/mol |  |
| Propiomazine is an antagonist at types 1, 2, and 4 dopamine receptors, serotonin (5-HT) receptor types 2A and 2C, muscarinic receptors 1 through 5, alpha(1)-receptors,...more Number of Targets: 14 |
| T3D1179 | Uranyl chloride 7791-26-6 | Cl2O2U 340.934 g/mol |  |
| Uranium is combined with either bicarbonate or a plasma protein in the blood but once in the kidney, it is released and forms complexes with phosphate ligands and prot...more Number of Targets: 1 |
| T3D3824 | Diclofop-methyl 51338-27-3 | C16H14Cl2O4 341.186 g/mol |  |
| Not Available Number of Targets: 11 |
| T3D4113 | Aristolochic acid 313-67-7 | C17H11NO7 341.272 g/mol |  |
| The carcinogenic and mutagenic effects associated with the binding of metabolites of ingested aristolochic acid (AA) to DNA have been extensively described in vitro an...more Number of Targets: 1 |
| T3D2864 | Naltrexone 16590-41-3 | C20H23NO4 341.401 g/mol |  |
| Naltrexone is a pure opiate antagonist and has little or no agonist activity. The mechanism of action of naltrexone in alcoholism is not understood; however, involveme...more Number of Targets: 7 |
| T3D4027 | (S)-Isocorydine 475-67-2 | C20H23NO4 341.401 g/mol |  |
| Isocorydine induces G2/M phase arrest by increasing cyclin B1 and p-CDK1 expression levels, which was caused by decreasing the expression and inhibiting the activation...more Number of Targets: 1 |
| T3D3929 | Tepraloxydim 149979-41-9 | C17H24ClNO4 341.830 g/mol |  |
| Not Available Number of Targets: 3 |
| T3D0675 | Dicobalt octacarbonyl 10210-68-1 | C8Co2O8 341.947 g/mol |  |
| Cobalt is believed to exhibit its toxicity through a oxidant-based and free radical-based processes. It produces oxygen radicals and may be oxidized to ionic cobalt, c...more Number of Targets: 35 |
| T3D1522 | Aluminium sulfate 10043-01-3 | Al2O12S3 342.151 g/mol |  |
| The main target organs of aluminum are the central nervous system and bone. Aluminum binds with dietary phosphorus and impairs gastrointestinal absorption of phosphoru...more Number of Targets: 3 |
| T3D3910 | Propiconazole 60207-90-1 | C15H17Cl2N3O2 342.220 g/mol |  |
| Propiconazole can decrease cholesterol levels that may cause polyploidy and disruption of mitotic cell cycling. It down-regulates the PTEN pathway and up-regulates the...more Number of Targets: 28 |
| T3D3934 | Thiophanate-methyl 23564-05-8 | C12H14N4O4S2 342.394 g/mol |  |
| Not Available Number of Targets: 11 |
| T3D1838 | Silver selenite 7784-05-6 | Ag2O3Se 342.690 g/mol |  |
| Selenium readily substitutes for sulfur in biomolecules and in many biochemical reactions, especially when the concentration of selenium is high and the concentration ...more Number of Targets: 17 |
| T3D4584 | Etizolam 40054-69-1 | C17H15ClN4S 342.846 g/mol |  |
| Benzodiazepines bind nonspecifically to benzodiazepine receptors BNZ1, which mediates sleep, and BNZ2, which affects affects muscle relaxation, anticonvulsant activity...more Number of Targets: 18 |
| T3D3800 | Boscalid 188425-85-6 | C18H12Cl2N2O 343.207 g/mol |  |
| Not Available Number of Targets: 12 |
| T3D2564 | Triazolam 28911-01-5 | C17H12Cl2N4 343.210 g/mol |  |
| Benzodiazepines bind nonspecifically to bezodiazepine receptors BNZ1, which mediates sleep, and BNZ2, which affects affects muscle relaxation, anticonvulsant activity,...more Number of Targets: 23 |
| T3D3560 | Gadolinium nitrate 10168-81-7 | GdN3O9 343.260 g/mol |  |
| Nitrate's toxicity is a result of it's conversion to nitrite once in the body. Nitrite causes the autocatalytic oxidation of oxyhemoglobin to hydrogen peroxide and met...more Number of Targets: 9 |