Browsing Toxins
Displaying toxin 1876 - 1900 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D2438 | 3,4,6-Trichlorodibenzofuran 83704-43-2 | C12H5Cl3O 271.527 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2439 | 3,4,7-Trichlorodibenzofuran 83704-44-3 | C12H5Cl3O 271.527 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2440 | 3,4,8-Trichlorodibenzofuran 83704-45-4 | C12H5Cl3O 271.527 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2441 | 3,4,9-Trichlorodibenzofuran 83704-46-5 | C12H5Cl3O 271.527 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2238 | 2,3,4-Trichlorodibenzofuran 57117-34-7 | C12H5Cl3O 271.527 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2241 | 2,3,6-Trichlordibenzofuran 57117-33-6 | C12H5Cl3O 271.527 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2244 | 2,3,7-Trichlorodibenzofuran 58802-17-8 | C12H5Cl3O 271.527 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2245 | 2,3,8-Trichlorodibenzofuran 57117-32-5 | C12H5Cl3O 271.527 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2249 | 2,4,6-Trichlorodibenzofuran 58802-14-5 | C12H5Cl3O 271.527 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2250 | 2,4,8-Trichlorodibenzofuran 54589-71-8 | C12H5Cl3O 271.527 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D0972 | Formparanate 17702-57-7 | C12H18ClN3O2 271.743 g/mol |  |
| Formparanate is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylation of the active sit...more Number of Targets: 2 |
| T3D2669 | Zoledronate 118072-93-8 | C5H10N2O7P2 272.090 g/mol |  |
| The action of zoledronate on bone tissue is based partly on its affinity for hydroxyapatite, which is part of the mineral matrix of bone. Zoledronate also targets farn...more Number of Targets: 4 |
| T3D0369 | Cadmium bromide 7789-42-6 | Br2Cd 272.219 g/mol |  |
| Cadmium initially binds to metallothionein and is transported to the kidney. Toxic effects are observed once the concentration of cadmium exceeds that of available met...more Number of Targets: 25 |
| T3D3728 | Alternariol methyl ether 23452-05-3 | C15H12O5 272.253 g/mol |  |
| Alternariol methyl ether has been shown to have genotoxic and mutagenic properties. It has demonstrated DNA-damaging activities such as single-strand and double-strand...more Number of Targets: 4 |
| T3D4832 | 17a-Estradiol 57-91-0 | C18H24O2 272.382 g/mol |  |
| Not Available Number of Targets: 9 |
| T3D4668 | Estradiol 50-28-2 | C18H24O2 272.382 g/mol |  |
| Estradiol enters target cells freely (e.g., female organs, breasts, hypothalamus, pituitary) and interacts with a target cell receptor. When the estrogen receptor has ...more Number of Targets: 8 |
| T3D0165 | Hexachlorocyclopentadiene 77-47-4 | C5Cl6 272.772 g/mol |  |
| HCCPD may interact with the microsomes that binds to secretory molecules and changes their ability to be transported from the cell. It can be postulated, that some of ...more Number of Targets: 42 |
| T3D2751 | Tolcapone 134308-13-7 | C14H11NO5 273.241 g/mol |  |
| Tolcapone hepatoxicity can be attributed to elevated levels of transminases, but studies have shown that minimal risk exists for those without preexisting liver condit...more Number of Targets: 1 |
| T3D2876 | Modafinil 68693-11-8 | C15H15NO2S 273.350 g/mol |  |
| The exact mechanism of action is unclear, although in vitro studies have shown it to inhibit the reuptake of dopamine by binding to the dopamine reuptake pump, and lea...more Number of Targets: 2 |
| T3D3009 | Chlormezanone 80-77-3 | C11H12ClNO3S 273.736 g/mol |  |
| Chlormezanone binds to central benzodiazepine receptors which interact allosterically with GABA receptors. This potentiates the effects of the inhibitory neurotransmit...more Number of Targets: 1 |
| T3D1169 | Uranium trioxide 1344-58-6 | H4O2U 274.060 g/mol |  |
| Uranium is combined with either bicarbonate or a plasma protein in the blood but once in the kidney, it is released and forms complexes with phosphate ligands and prot...more Number of Targets: 1 |
| T3D4491 | Cyclanilide 113136-77-9 | C11H9Cl2NO3 274.100 g/mol |  |
| Not Available Number of Targets: 21 |
| T3D0921 | Allyxycarb 6392-46-7 | C16H22N2O2 274.358 g/mol |  |
| Allyxycarb is a cholinesterase or acetylcholinesterase (AChE) inhibitor. Carbamates form unstable complexes with chlolinesterases by carbamoylation of the active sites...more Number of Targets: 2 |
| T3D3810 | Cinmethylin 87818-31-3 | C18H26O2 274.398 g/mol |  |
| Cinmethylin is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholinest...more Number of Targets: 9 |
| T3D2741 | Ropivacaine 84057-95-4 | C17H26N2O 274.401 g/mol |  |
| Local anesthetics such as Ropivacaine block the generation and the conduction of nerve impulses, presumably by increasing the threshold for electrical excitation in th...more Number of Targets: 1 |