Browsing Toxins
Displaying toxin 2401 - 2425 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D2087 | 1,3,6,9-Tetrachlorodibenzo-p-dioxin 71669-24-4 | C12H4Cl4O2 321.971 g/mol |  |
| CDDs cause their toxic effects by binding to the aryl hydrocarbon receptor and subsequently altering the trascription of certain genes. The affinity for the Ah recepto...more Number of Targets: 4 |
| T3D2088 | 1,3,7,8-Tetrachlorodibenzo-p-dioxin 50585-46-1 | C12H4Cl4O2 321.971 g/mol |  |
| CDDs cause their toxic effects by binding to the aryl hydrocarbon receptor and subsequently altering the trascription of certain genes. The affinity for the Ah recepto...more Number of Targets: 4 |
| T3D2089 | 1,3,7,9-Tetrachlorodibenzo-p-dioxin 62470-53-5 | C12H4Cl4O2 321.971 g/mol |  |
| CDDs cause their toxic effects by binding to the aryl hydrocarbon receptor and subsequently altering the trascription of certain genes. The affinity for the Ah recepto...more Number of Targets: 4 |
| T3D2090 | 1,4,6,9-Tetrachlorodibenzo-p-dioxin 40581-93-9 | C12H4Cl4O2 321.971 g/mol |  |
| CDDs cause their toxic effects by binding to the aryl hydrocarbon receptor and subsequently altering the trascription of certain genes. The affinity for the Ah recepto...more Number of Targets: 4 |
| T3D2091 | 1,4,7,8-Tetrachlorodibenzo-p-dioxin 40581-94-0 | C12H4Cl4O2 321.971 g/mol |  |
| CDDs cause their toxic effects by binding to the aryl hydrocarbon receptor and subsequently altering the trascription of certain genes. The affinity for the Ah recepto...more Number of Targets: 4 |
| T3D0073 | 2,3,7,8-Tetrachlorodibenzo-p-dioxin 1746-01-6 | C12H4Cl4O2 321.971 g/mol |  |
| CDDs bind to the aryl hydrocarbon (Ah) receptor and subsequently alter the transcription of several genes (oncogenes, growth factors, receptors, hormones, and drug-met...more Number of Targets: 2 |
| T3D3675 | Zeranol 26538-44-3 | C18H26O5 322.396 g/mol |  |
| Zeranol acts as an agonist at the estrogen receptors, interfering with the binding of natural estrogens. This disrupts hormone levels and affects a number of signaling...more Number of Targets: 9 |
| T3D4071 | Gelsemine 509-15-9 | C20H22N2O2 322.401 g/mol |  |
| Gelsemine has convulsant effects with a similar mechanism of action to strychnine. Strychnine is a neurotoxin which acts as an antagonist of glycine and acetylcholine ...more Number of Targets: 0 |
| T3D3808 | Chlorpyrifos-methyl 5598-13-0 | C7H7Cl3NO3PS 322.533 g/mol |  |
| Chlorpyrifos-methyl is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylc...more Number of Targets: 4 |
| T3D3954 | Chloramphenicol 56-75-7 | C11H12Cl2N2O5 323.129 g/mol |  |
| Chloramphenicol targets the large 39S subunit of the mitochondrial ribosome thereby deactivation mitochondrial protein synthesis. As a result chloramphenicol is cytoto...more Number of Targets: 2 |
| T3D0325 | Lead chromate 7758-97-6 | CrO4Pb 323.200 g/mol |  |
| Lead mimics other biologically important metals, such as zinc, calcium, and iron, competing as cofactors for many of their respective enzymatic reactions. For example,...more Number of Targets: 34 |
| T3D3852 | Flutolanil 66332-96-5 | C17H16F3NO2 323.310 g/mol |  |
| Not Available Number of Targets: 11 |
| T3D0786 | Lead thiocyanate 592-87-0 | C2N2PbS2 323.400 g/mol |  |
| Lead mimics other biologically important metals, such as zinc, calcium, and iron, competing as cofactors for many of their respective enzymatic reactions. For example,...more Number of Targets: 68 |
| T3D0338 | Tetraethyl lead 78-00-2 | C8H20Pb 323.400 g/mol |  |
| Lead mimics other biologically important metals, such as zinc, calcium, and iron, competing as cofactors for many of their respective enzymatic reactions. For example,...more Number of Targets: 29 |
| T3D3582 | Lysergic Acid Diethylamide 50-37-3 | C20H25N3O 323.432 g/mol |  |
| LSD preferentially inhibits serotonergic cell firing by acting as an agonist at the 5-HT1A receptors in the raphe nuclei, locus coeruleus, and cortex. It also acts as ...more Number of Targets: 17 |
| T3D0872 | Antimony pentoxide 1314-60-9 | O5Sb2 323.520 g/mol |  |
| The inhalation data suggest that the myocardium is a target of antimony toxicity. It is possible that antimony affects circulating glucose by interfering with enzymes ...more Number of Targets: 20 |
| T3D3663 | Sterigmatocystin 10048-13-2 | C18H12O6 324.284 g/mol |  |
| Sterigmatocystin's carcinogenic properties are a result of its ability to form guanyl DNA adducts and bind to DNA. In addition, DNA adduct formation causes enhanced pr...more Number of Targets: 3 |
| T3D3542 | Valaciclovir 124832-26-4 | C13H20N6O4 324.336 g/mol |  |
| Valaciclovir is phosphorylated by viral thymidine kinase to acyclovir triphosphate (the active metabolite) which then inhibits herpes viral DNA replication by competit...more Number of Targets: 0 |
| T3D3698 | 3-Acetoxyscirpene-4,15-diol 70402-13-0 | C17H24O6 324.369 g/mol |  |
| Unlike many other mycotoxins, trichothecenes do not require metabolic activation to exert their biological activity, instead directly reacting with cellular components...more Number of Targets: 2 |
| T3D3699 | Monoacetoxyscirpenol 2623-22-5 | C17H24O6 324.369 g/mol |  |
| Unlike many other mycotoxins, trichothecenes do not require metabolic activation to exert their biological activity, instead directly reacting with cellular components...more Number of Targets: 2 |
| T3D2715 | Citalopram 59729-33-8 | C20H21FN2O 324.392 g/mol |  |
| The antidepressant, antiobsessive-compulsive, and antibulimic actions of citalopram are presumed to be linked to its inhibition of CNS neuronal uptake of serotonin. Ci...more Number of Targets: 14 |
| T3D3007 | Escitalopram 128196-01-0 | C20H21FN2O 324.392 g/mol |  |
| The antidepressant, antiobsessive-compulsive, and antibulimic actions of escitalopram are presumed to be linked to its inhibition of CNS neuronal uptake of serotonin. ...more Number of Targets: 6 |
| T3D2800 | Quinine 130-95-0 | C20H24N2O2 324.417 g/mol |  |
| The theorized mechanism of action for quinine and related anti-malarial drugs is that these drugs are toxic to the malaria parasite. Specifically, the drugs interfere ...more Number of Targets: 3 |
| T3D3794 | Azamethiphos 35575-96-3 | C9H10ClN2O5PS 324.678 g/mol |  |
| Azamethiphos is a cholinesterase or acetylcholinesterase (AChE) inhibitor. A cholinesterase inhibitor (or 'anticholinesterase') suppresses the action of acetylcholines...more Number of Targets: 11 |
| T3D4490 | Cyazofamid 120116-88-3 | C13H13ClN4O2S 324.786 g/mol |  |
| Organic nitriles decompose into cyanide ions both in vivo and in vitro. Consequently the primary mechanism of toxicity for organic nitriles is their production of toxi...more Number of Targets: 24 |