Browsing Toxins
Displaying toxin 2426 - 2450 of 3678 in total
| T3DB ID | Name CAS Number | Formula Weight | Structure | Type | Mechanism of Toxicity |
|---|---|---|---|---|---|
| T3D3054 | Prazepam 2955-38-6 | C19H17ClN2O 324.804 g/mol |  |
| Prazepam is believed to stimulate GABA receptors in the ascending reticular activating system. Since GABA is inhibitory, receptor stimulation increases inhibition and ...more Number of Targets: 18 |
| T3D0617 | Chlorbenzylate 510-15-6 | C16H14Cl2O3 325.187 g/mol |  |
| At least four mechanisms, possibly all functioning simultaneously.
DDT reduces potassium transport across the membrane. DDT alters the porous channels through which s...more Number of Targets: 47 |
| T3D3845 | Flumetsulam 98967-40-9 | C12H9F2N5O2S 325.294 g/mol |  |
| Not Available Number of Targets: 1 |
| T3D0319 | Lead acetate 301-04-2 | C4H6O4Pb 325.300 g/mol |  |
| Lead mimics other biologically important metals, such as zinc, calcium, and iron, competing as cofactors for many of their respective enzymatic reactions. For example,...more Number of Targets: 30 |
| T3D3685 | Ergonovine 60-79-7 | C19H23N3O2 325.405 g/mol |  |
| Ergoline alkaloids tend to act as a group, producing complex and variable effects of partial agonism or antagonism at adrenergic, dopaminergic, and serotonergic recept...more Number of Targets: 10 |
| T3D1243 | Tributyltin chloride 1461-22-9 | C12H27ClSn 325.510 g/mol |  |
| Organotin compounds produce neurotoxic and immunotoxic effects. Organotins may directly activate glial cells contributing to neuronal cell degeneration by local releas...more Number of Targets: 40 |
| T3D2859 | Midazolam 59467-70-8 | C18H13ClFN3 325.767 g/mol |  |
| It is thought that the actions of benzodiazepines such as midazolam are mediated through the inhibitory neurotransmitter gamma-aminobutyric acid (GABA), which is one o...more Number of Targets: 23 |
| T3D2258 | 2,7-Dibromodibenzofuran 65489-80-7 | C12H6Br2O 325.983 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D2263 | 2,8-Dibromodibenzofuran 10016-52-1 | C12H6Br2O 325.983 g/mol |  |
| Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso...more Number of Targets: 2 |
| T3D4496 | Diniconazole 83657-24-3 | C15H17Cl2N3O 326.221 g/mol |  |
| Not Available Number of Targets: 15 |
| T3D3604 | Gliotoxin 67-99-2 | C13H14N2O4S2 326.391 g/mol |  |
| Gliotoxin possesses immunosuppressive properties as it may suppress and cause apoptosis in certain types of cells of the immune system, including neutrophils, eosinop...more Number of Targets: 12 |
| T3D0511 | 2,3,3',4',5'-Pentachlorobiphenyl 76842-07-4 | C12H5Cl5 326.433 g/mol |  |
| The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcriptio...more Number of Targets: 7 |
| T3D0512 | 2,3',4,4',5'-Pentachlorobiphenyl 65510-44-3 | C12H5Cl5 326.433 g/mol |  |
| The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcriptio...more Number of Targets: 7 |
| T3D0513 | 2,3',4',5,5'-Pentachlorobiphenyl 70424-70-3 | C12H5Cl5 326.433 g/mol |  |
| The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcriptio...more Number of Targets: 7 |
| T3D0514 | 2,3',4',5',6-Pentachlorobiphenyl 74472-39-2 | C12H5Cl5 326.433 g/mol |  |
| The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcriptio...more Number of Targets: 7 |
| T3D0515 | 3,3',4,4',5-Pentachlorobiphenyl 57465-28-8 | C12H5Cl5 326.433 g/mol |  |
| The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcriptio...more Number of Targets: 8 |
| T3D0516 | 3,3',4,5,5'-Pentachlorobiphenyl 39635-33-1 | C12H5Cl5 326.433 g/mol |  |
| The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcriptio...more Number of Targets: 7 |
| T3D0013 | Aroclor 1254 11097-69-1 | C12H5Cl5 326.433 g/mol |  |
| The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcriptio...more Number of Targets: 8 |
| T3D0472 | 2,2',3,3',5-Pentachlorobiphenyl 60145-20-2 | C12H5Cl5 326.433 g/mol |  |
| The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcriptio...more Number of Targets: 7 |
| T3D0473 | 2,2',3,3',6-Pentachlorobiphenyl 52663-60-2 | C12H5Cl5 326.433 g/mol |  |
| The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcriptio...more Number of Targets: 7 |
| T3D0474 | 2,2',3,4,4'-Pentachlorobiphenyl 65510-45-4 | C12H5Cl5 326.433 g/mol |  |
| The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcriptio...more Number of Targets: 7 |
| T3D0475 | 2,2',3,4,5-Pentachlorobiphenyl 55312-69-1 | C12H5Cl5 326.433 g/mol |  |
| The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcriptio...more Number of Targets: 7 |
| T3D0476 | 2,2',3,4,5'-Pentachlorobiphenyl 38380-02-8 | C12H5Cl5 326.433 g/mol |  |
| The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcriptio...more Number of Targets: 7 |
| T3D0477 | 2,2',3,4,6-Pentachlorobiphenyl 55215-17-3 | C12H5Cl5 326.433 g/mol |  |
| The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcriptio...more Number of Targets: 7 |
| T3D0478 | 2,2',3,4,6'-Pentachlorobiphenyl 73575-57-2 | C12H5Cl5 326.433 g/mol |  |
| The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcriptio...more Number of Targets: 7 |